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Each day, the radiotherapy departments of large hospitals must plan numerous irradiation sessions, considering the availability of human and material resources, such as healthcare professionals and linear accelerators. With the increasing number of patients suffering from different types of cancers, manually establishing schedules following each patient\u2019s treatment protocols has become an extremely difficult and time-consuming task. We propose an optimization algorithm that automatically schedules and generates patient appointments. The model can rearrange fixed appointments to accommodate urgent cases, enabling hospitals to schedule appointments more efficiently. It respects the different treatment protocols and should increase staff and patient satisfaction. The optimization algorithm can be connected to a mobile application allowing patients to accept or refuse appointment changes for rescheduling radiotherapy treatments.<\/jats:p>","DOI":"10.1177\/14604582251318252","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T04:04:57Z","timestamp":1739765097000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Radiotherapy department supported by an optimization algorithm for scheduling patient appointments"],"prefix":"10.1177","volume":"31","author":[{"given":"Chavez","family":"Marcela","sequence":"first","affiliation":[{"name":"Li\u00e8ge University Hospital, Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2095-3338","authenticated-orcid":false,"given":"Gonzalez","family":"Silvia","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Castilla y Le\u00f3n, Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiz","family":"Alvaro","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Castilla y Le\u00f3n, Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duflot","family":"Patrick","sequence":"additional","affiliation":[{"name":"Li\u00e8ge University Hospital, Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Jansen","sequence":"additional","affiliation":[{"name":"Li\u00e8ge University Hospital, Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izidor","family":"Mlakar","sequence":"additional","affiliation":[{"name":"University of Maribor, Maribor, Slovenija"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6476-4494","authenticated-orcid":false,"given":"Umut","family":"Arioz","sequence":"additional","affiliation":[{"name":"University of Maribor, Maribor, Slovenija"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentino","family":"Safran","sequence":"additional","affiliation":[{"name":"University of Maribor, Maribor, Slovenija"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kolh","family":"Philippe","sequence":"additional","affiliation":[{"name":"Li\u00e8ge University Hospital, Li\u00e8ge, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3062-8088","authenticated-orcid":false,"given":"Van Gasteren","family":"Marteyn","sequence":"additional","affiliation":[{"name":"Instituto Tecnol\u00f3gico de Castilla y Le\u00f3n, Burgos, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"key":"bibr1-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33588"},{"key":"bibr2-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1002\/1878-0261.12690"},{"key":"bibr3-14604582251318252","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12134502"},{"key":"bibr4-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.04.171"},{"key":"bibr5-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1093\/intqhc\/mzac014"},{"key":"bibr6-14604582251318252","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11050639"},{"key":"bibr7-14604582251318252","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182111337"},{"key":"bibr8-14604582251318252","author":"Demir NB","year":"2019","journal-title":"Middle East Technical University, Graduate School of Natural and Applied Sciences"},{"key":"bibr9-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1016\/j.cor.2021.105230"},{"issue":"3","key":"bibr10-14604582251318252","first-page":"263","volume":"6","author":"Conforti D","year":"2008","journal-title":"Springer Nature"},{"key":"bibr11-14604582251318252","first-page":"201","volume-title":"Proceedings of the Eighteenth International Conference on Systems Engineering (ICSE2006)","author":"Kapamara T","year":"2006"},{"key":"bibr12-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1007\/s10951-011-0239-8"},{"key":"bibr13-14604582251318252","first-page":"3391","author":"Burke EK","year":"2011","journal-title":"CoRR"},{"key":"bibr14-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-02976-9_14"},{"key":"bibr15-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-016-0390-4"},{"key":"bibr16-14604582251318252","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.09.006"},{"key":"bibr17-14604582251318252","unstructured":"Leite-Rocha P. 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