{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T13:00:46Z","timestamp":1774098046268,"version":"3.50.1"},"reference-count":25,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthod"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>During the course of orthodontic treatment, a proper hygiene protocol is advised to all patients. Maintenance of oral hygiene prevents potential damage to hard tissue along with soft tissue. Despite preventive oral hygiene measures during fixed orthodontic therapy, some patients develop white spot lesions (WSL), compromising aesthetics and posing a potential risk of developing a carious lesion. Tooth remineralisation using calcium, fluoride, phosphate and other biocompatible agents is a potential solution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>This study aimed to compare the remineralising potential of Remin Pro (hydroxyapatite), Sensodyne Pronamel (sodium fluoride) and Pur O3 Olive (ozonated olive oil) on artificially created WSLs using quantitative light-induced fluorescence (QLF) and polarised light microscopy (PLM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>An in vitro study was conducted over 1 year using 75 extracted premolars, divided into three groups (n = 25). Artificial carious lesions were created with a demineralising solution, followed by a 21-day pH cycling regime with respective agents. QLF assessed lesion volume (\u2206Q), fluorescence loss (\u2206F) and maximum fluorescence loss (\u2206F Max), while PLM was used to evaluate the enamel subsurface changes qualitatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Statistically significant improvements were noted in \u2206Q, \u2206F and \u2206F Max across all groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001). Intergroup comparison revealed highly significant changes from pre-test to post-test (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001). There was no statistically significant difference in treatment effect between Remin Pro and Pur O3 Olive.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Remin Pro demonstrated greater remineralisation potential compared to Sensodyne Pronamel and Pur O3 Olive under in vitro conditions. There was no statistically significant difference in treatment effect between Remin Pro and Pur O3 Olive.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14653125251408858","type":"journal-article","created":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T17:26:04Z","timestamp":1769621164000},"page":"74-83","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the efficacy of ozonated olive oil over commercially available toothpastes in remineralisation of white spot lesions: An in vitro study"],"prefix":"10.1177","volume":"53","author":[{"given":"Raghunath","family":"N","sequence":"first","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Namrata","family":"Gaur","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjana","family":"Shetty","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghavendra","family":"Shanbhog","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyothikiran","family":"H","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopaedics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5204-8178","authenticated-orcid":false,"given":"Vidya G","family":"Doddawad","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research, Mysuru, KA, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,28]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-3335"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19095629"},{"issue":"6","key":"e_1_3_2_4_1","first-page":"192","article-title":"Evaluation of different fluoridated dentifrice formulations using an in situ erosion remineralisation model","volume":"20","author":"Barlow AP","year":"2009","unstructured":"Barlow AP, Sufi F, Mason SC (2009) Evaluation of different fluoridated dentifrice formulations using an in situ erosion remineralisation model. Journal of Clinical Dentistry 20(6): 192\u2013198.","journal-title":"Journal of Clinical Dentistry"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2014.980846"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-025-06234-3"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.21608\/eos.2012.78852"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12013"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03610-z"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ocr.12888"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.2319\/100107-468.1"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.105220"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12903-023-03720-6"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2025.105686"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph192214967"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17239106"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10266-021-00675-4"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2024.104973"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijdr.ijdr_704_22"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/jos.JOS_46_20"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.13381"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.15171\/joddd.2019.006"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000260599"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.3892\/br.2024.1803"},{"issue":"3","key":"e_1_3_2_25_1","article-title":"Fluoride toothpastes of different concentrations for preventing dental caries","volume":"3","author":"Walsh T","year":"2019","unstructured":"Walsh T, Worthington HV, Glenny AM, et al. (2019) Fluoride toothpastes of different concentrations for preventing dental caries. Cochrane Database of Systematic Reviews 3(3): CD007868.","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.17219\/dmp\/140964"}],"container-title":["Journal of Orthodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14653125251408858","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/14653125251408858","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14653125251408858","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T12:30:25Z","timestamp":1774096225000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/14653125251408858"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,28]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/14653125251408858"],"URL":"https:\/\/doi.org\/10.1177\/14653125251408858","relation":{},"ISSN":["1465-3125","1465-3133"],"issn-type":[{"value":"1465-3125","type":"print"},{"value":"1465-3133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,28]]}}}