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This case report emphasizes the fetal renal impact of prolonged intrauterine exposure to renin-angiotensin system (RAS) blockers, and highlights that this exposure can cause severe prenatal hypocalvaria. This delayed ossification can be reversible after birth, but the presence of anhydramnios indicates an early and irreversible block of RAS blockers in the fetus that is responsible for fetal kidney development abnormalities. This association carries a high risk of neonatal death. Prolonged exposure to ARA II or other RAS blockers remains prohibited throughout pregnancy.<\/jats:p>","DOI":"10.1177\/1470320318810940","type":"journal-article","created":{"date-parts":[[2018,11,4]],"date-time":"2018-11-04T22:54:24Z","timestamp":1541372064000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Prenatal hypocalvaria after prolonged intrauterine exposure to angiotensin II receptor antagonists"],"prefix":"10.1177","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3341-5267","authenticated-orcid":false,"given":"Marine","family":"Lallemant","sequence":"first","affiliation":[{"name":"Obstetrics and Gynaecology Department, Besan\u00e7on University Medical Centre, Franche-Comt\u00e9 University, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Pr\u00e9vost","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology Department, 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