{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:42:24Z","timestamp":1777725744850,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2002,2,1]],"date-time":"2002-02-01T00:00:00Z","timestamp":1012521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2002,2]]},"abstract":"<jats:p>\n                    Beh\u00e7et's disease is a systemic vasculitis of unknown aetiology. Endothelial cell injury plays an important role in the pathogenesis and immunopathology of systemic vasculitises, but an immunopathogenic basis is also probable in Beh\u00e7et's disease. E-selectin is an indicator of endothelial injury, and \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    -microglobulin (\u03b2\n                    <jats:sub>2<\/jats:sub>\n                    M) is increased in immunological disorders. The serum concentrations of these two markers were determined in 40 patients with active Beh\u00e7et's disease and 40 healthy controls. E-selectin was determined by enzyme-linked immunosorbent assay and \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    M was determined by the nephelometric method. The mean (\u00b1 SD) serum concentration of E-selectin was 122.13 \u00b1 62.32 ng\/ml and that of \u03b2\n                    <jats:sub>2<\/jats:sub>\n                    M was 0.31 \u00b1 0.05 mg\/dl. Both concentrations were statistically significantly increased in patients with Beh\u00e7et's disease compared with controls. More comprehensive studies are needed to determine whether these parameters are useful indicators of the activity of Beh\u00e7et's disease.\n                  <\/jats:p>","DOI":"10.1177\/147323000203000113","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:22:28Z","timestamp":1361974948000},"page":"85-88","source":"Crossref","is-referenced-by-count":5,"title":["Serum E-Selectin and \u03b2\n                    <sub>2<\/sub>\n                    -Microglobulin Levels in Beh\u00e7et's Disease"],"prefix":"10.1177","volume":"30","author":[{"given":"A","family":"Karakuzu","sequence":"first","affiliation":[{"name":"Department of Dermatology, Ataturk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Akta\u015f","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ataturk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F","family":"Ak\u00e7jay","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medicine, Ataturk University, Erzurum, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2002,2,1]]},"reference":[{"key":"bibr1-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(96)00230-6"},{"key":"bibr2-147323000203000113","first-page":"1428","volume":"17","author":"Hamzaoui K","year":"1990","journal-title":"J Rheumatol"},{"key":"bibr3-147323000203000113","first-page":"247","volume":"49","author":"Niwa Y","year":"1982","journal-title":"Clin Exp Immunol"},{"key":"bibr4-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1982.tb02386.x"},{"key":"bibr5-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1136\/ard.55.2.128"},{"key":"bibr6-147323000203000113","first-page":"126","volume":"71","author":"Hamzaoui K","year":"1988","journal-title":"Clin Exp Immunol"},{"key":"bibr7-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1984.tb05658.x"},{"key":"bibr8-147323000203000113","first-page":"7","volume":"21","author":"Kansu E","year":"1987","journal-title":"Deri Hast Frengi Ar\u015f"},{"key":"bibr9-147323000203000113","first-page":"98","volume":"5","author":"D\u00fczg\u00fcn N","year":"1995","journal-title":"MN Klinik Bilimler"},{"key":"bibr10-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1126\/science.1439808"},{"key":"bibr11-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90393-D"},{"key":"bibr12-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)47274-7"},{"key":"bibr13-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb16946.x"},{"key":"bibr14-147323000203000113","first-page":"370","volume-title":"Dermatology in General Medicine","author":"Duvic M","year":"1999","edition":"5"},{"key":"bibr15-147323000203000113","first-page":"327","volume":"9","author":"Sensi A","year":"1991","journal-title":"Dis Markers"},{"key":"bibr16-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(87)90896-5"},{"key":"bibr17-147323000203000113","first-page":"994","volume-title":"Clinical Chemistry","author":"Statland BE","year":"1996"},{"key":"bibr18-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1111\/j.1348-0421.1990.tb01071.x"},{"key":"bibr19-147323000203000113","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-9842(00)00148-3"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000203000113","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000203000113","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:43:16Z","timestamp":1777459396000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/147323000203000113"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,2]]}},"alternative-id":["10.1177\/147323000203000113"],"URL":"https:\/\/doi.org\/10.1177\/147323000203000113","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,2]]}}}