{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:33:36Z","timestamp":1777725216345,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2009,2]]},"abstract":"This study examined the diagnostic accuracy of nine indices to discriminate between patients with mild-to-moderate (haemoglobin 8.5 \u2212 11 g\/dl) or moderate-to-severe (haemoglobin < 8.5 g\/dl) iron deficiency anaemia (IDA) from those with \u03b2-thalassaemia (\u03b2-TT) ( n = 100 per group). Indices examined were red blood cell (RBC) count, RBC distribution width (RDW), Mentzer index (MI), Shine and Lal index (S&L), England and Fraser index (E&F), Srivastava index (S), Green and King index (G&K), RDW index (RDWI), and Ricerca index (R). Index sensitivity, specificity, and positive and negative prognostic values were examined. Youden's indices were calculated and showed: S&L > G&K > E&F > RBC = RDWI > MI > S > R > RDW to differentiate between \u03b2-TT and mild-to-moderate IDA; and S&L > G&K > E&F = RDWI > RBC > R > MI > S > RDW to differentiate between \u03b2-TT or moderate-to-severe IDA. For both groups, S&L and G&K offered the best discrimination and RDW the worst. S&L showed the highest Youden index for \u03b2-TT and IDA discrimination, but sensitivity and specificity were not 100%. In both mild and severe IDA, the S&L index may be used to differentiate cases of \u03b2-TT from IDA cases, but large clinical trials are needed to explore this further.<\/jats:p>","DOI":"10.1177\/147323000903700103","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:22:43Z","timestamp":1361974963000},"page":"25-30","source":"Crossref","is-referenced-by-count":33,"title":["Red Cell Indices and Functions Differentiating Patients with the \u03b2-Thalassaemia Trait from those with Iron Deficiency Anaemia"],"prefix":"10.1177","volume":"37","author":[{"given":"V","family":"Okan","sequence":"first","affiliation":[{"name":"Gaziantep University School of Medicine, Department of Haematology, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Cigiloglu","sequence":"additional","affiliation":[{"name":"Gaziantep University School of Medicine, Department of Haematology, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Cifci","sequence":"additional","affiliation":[{"name":"Gaziantep University School of Medicine, Department of Haematology, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Gaziantep University School of Medicine, Department of Haematology, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Pehlivan","sequence":"additional","affiliation":[{"name":"Gaziantep University School of Medicine, Department of Haematology, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,2,1]]},"reference":[{"key":"bibr1-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1159\/000208641"},{"key":"bibr2-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1080\/08880010600683400"},{"key":"bibr3-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(77)92128-6"},{"key":"bibr4-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91856-4"},{"key":"bibr5-147323000903700103","first-page":"481","volume":"15","author":"Green R","year":"1989","journal-title":"Blood Cells"},{"key":"bibr6-147323000903700103","first-page":"409","volume":"72","author":"Ricerca BM","year":"1987","journal-title":"Haematologica"},{"key":"bibr7-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)90637-5"},{"key":"bibr8-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91446-3"},{"key":"bibr9-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-200X.2002.01636.x"},{"key":"bibr10-147323000903700103","first-page":"615","volume":"36","author":"Yeo GS","year":"1995","journal-title":"Singapore Med J"},{"key":"bibr11-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/106.2.201"},{"key":"bibr12-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-553X.2007.00966.x"},{"key":"bibr13-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2007.00853.x"},{"key":"bibr14-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-007-0302-x"},{"key":"bibr15-147323000903700103","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fml070"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000903700103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000903700103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:41:48Z","timestamp":1777459308000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/147323000903700103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["10.1177\/147323000903700103"],"URL":"https:\/\/doi.org\/10.1177\/147323000903700103","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}