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It included 22 children with SSPE aged 2-15 years (patient group) and 22 age- and gender-matched healthy children (control group). In children &lt; 6 years old, there were no statistically significant differences between the two groups in the proportions of lymphocytes expressing the surface markers CD3, CD8, CD19 or CD16\/56, or in CD4\/CD8 ratio. The proportion of CD4+ lymphocytes in SSPE patients &lt; 6 years of age was significantly lower compared with the control group. In children \u2265 6 years old, there were no significant differences in the lymphocyte subgroups. In conclusion, these findings suggest that a low CD4+ lymphocyte count might be responsible for SSPE in younger children.<\/jats:p>","DOI":"10.1177\/147323000903700326","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:22:43Z","timestamp":1361974963000},"page":"828-834","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Lymphocyte Subgroups in Children with Subacute Sclerosing Panencephalitis"],"prefix":"10.1177","volume":"37","author":[{"given":"C","family":"Yilmaz","sequence":"first","affiliation":[{"name":"Department of Paediatric Neurology, Faculty of Medicine, Mustafa Kemal University, Hatay, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"SA","family":"Yuca","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Faculty of Medicine, Y\u00fcz\u00fcnc\u00fc Yil University, Van, 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