{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:37:59Z","timestamp":1777725479135,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2009,10]]},"abstract":"<jats:p>This study was designed to investigate whether a correlation exists between amplification of the human telomerase gene (human telomerase RNA component [ TERC]) and high-risk human papillomavirus (HR-HPV) infection in 101 women with cervical intra-epithelial neoplasia (CIN). Eight patients (7.9%) had CIN 1, 24 (23.8%) had CIN 2 and 69 (68.3%) had CIN 3. TERC was amplified in 31.7% of all CIN patients. The difference in frequency of TERC amplification between patients with low-grade CIN (CIN 1) and those with high-grade CIN (CIN 2 and CIN 3) was not significant. HR-HPV infection was detected in 88.1% of all CIN cases and was significantly more frequent in patients with CIN 2 and CIN 3 than in patients with CIN 1. There was no significant difference in the frequency of HR-HPV infection between groups of patients with and without TERC amplification. In conclusion, this study found no correlation between TERC amplification and HR-HPV infection in patients with CIN.<\/jats:p>","DOI":"10.1177\/147323000903700537","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:22:43Z","timestamp":1361974963000},"page":"1588-1595","source":"Crossref","is-referenced-by-count":2,"title":["Human Telomerase Gene Amplification and High-Risk Human Papillomavirus Infection in Women with Cervical Intra-Epithelial Neoplasia"],"prefix":"10.1177","volume":"37","author":[{"given":"I","family":"Taka\u010d","sequence":"first","affiliation":[{"name":"Department of Gynaecological and Breast Oncology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Arko","sequence":"additional","affiliation":[{"name":"Department of Gynaecological and Breast Oncology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Kodri\u010d","sequence":"additional","affiliation":[{"name":"Department of Gynaecological and Breast Oncology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Poljak","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Zagorac","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, University Department of Gynaecology and Perinatology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Erjavec-\u0160kerget","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, University Department of Gynaecology and Perinatology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Kokalj-Voka\u010d","sequence":"additional","affiliation":[{"name":"Laboratory of Medical Genetics, University Department of Gynaecology and Perinatology, Maribor University Hospital, Maribor, Slovenia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,10,1]]},"reference":[{"key":"bibr1-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199304000-00018"},{"key":"bibr2-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1002\/path.2070"},{"key":"bibr3-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2264(199907)25:3<195::AID-GCC1>3.0.CO;2-8"},{"key":"bibr4-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.1.479"},{"key":"bibr5-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-4608(97)83452-8"},{"key":"bibr6-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1038\/350569a0"},{"key":"bibr7-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1080\/cmt.4.3.181.193"},{"key":"bibr8-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)62341-3"},{"key":"bibr9-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1038\/nrc798"},{"key":"bibr10-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/94.18.1406"},{"key":"bibr11-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.9.2934"},{"key":"bibr12-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.3.796-797.1999"},{"key":"bibr13-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviromet.2005.12.004"},{"key":"bibr14-147323000903700537","first-page":"147","volume":"14","author":"Poljak M","year":"2005","journal-title":"Acta Dermatovenerol Alp Pannonica Adriat"},{"key":"bibr15-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00634.x"},{"key":"bibr16-147323000903700537","first-page":"25","volume":"151","author":"Anderson S","year":"1997","journal-title":"Am J Pathol"},{"key":"bibr17-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.1.31"},{"key":"bibr18-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2000.19299"},{"key":"bibr19-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2006.00659.x"},{"key":"bibr20-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65627-1"},{"key":"bibr21-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603253"},{"key":"bibr22-147323000903700537","first-page":"849","volume":"43","author":"Jiang J","year":"2008","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"bibr23-147323000903700537","doi-asserted-by":"publisher","DOI":"10.1097\/01.pgp.0000250146.44592.d2"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000903700537","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323000903700537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:42:27Z","timestamp":1777459347000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/147323000903700537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["10.1177\/147323000903700537"],"URL":"https:\/\/doi.org\/10.1177\/147323000903700537","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,10]]}}}