{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T12:42:53Z","timestamp":1777725773881,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Int Med Res"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>This study investigated D-dimer levels in 241 patients admitted to the emergency department with sudden-onset chest pain. The patient group included those diagnosed with acute coronary syndrome (ACS; i.e. unstable angina pectoris [USAP], non-ST elevated myocardial infarction [NSTEMI], ST-elevated myocardial infarction [STEMI]); the control group included those diagnosed with non-cardiac chest pain. Mean serum levels of D-dimer, creatine kinase-MB (CK-MB) and troponin I (TPI) were compared between the groups. Levels of D-dimer, CK-MB and TPI in the patient group were significantly higher than in the control group. There were also significantly higher D-dimer, CK-MB and TPI levels in the STEMI and NSTEMI patient subgroups compared with the control group. Only the D-dimer level was significantly higher in the USAP subgroup versus the control group. The sensitivity and specificity of D-dimer for ACS were 83.7% and 95.4%, respectively, suggesting that evaluating D-dimer levels might be useful in the emergency room for diagnosing ACS and predicting mortality in patients presenting with acute chest pain.<\/jats:p>","DOI":"10.1177\/147323001003800523","type":"journal-article","created":{"date-parts":[[2013,2,27]],"date-time":"2013-02-27T14:22:55Z","timestamp":1361974975000},"page":"1772-1779","source":"Crossref","is-referenced-by-count":8,"title":["The Role of Serum D-Dimer Level in the Diagnosis of Patients Admitted to the Emergency Department Complaining of Chest Pain"],"prefix":"10.1177","volume":"38","author":[{"given":"M","family":"Orak","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, University of Dicle, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"\u00dcst\u00fcnda\u011f","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Dicle, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"G\u00fclo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Dicle, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6","family":"Alyan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Dicle, Diyarbakir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MB","family":"Sayhan","sequence":"additional","affiliation":[{"name":"Emergency Department, State Hospital, Edirne, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2010,10,1]]},"reference":[{"key":"bibr1-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2000.108823"},{"key":"bibr2-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(83)90508-8"},{"key":"bibr3-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)92192-V"},{"key":"bibr4-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.67.1.53"},{"key":"bibr5-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1097\/01.mbc.0000252594.93067.f8"},{"key":"bibr6-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1985.tb07476.x"},{"key":"bibr7-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20167"},{"key":"bibr8-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2003.88"},{"key":"bibr9-147323001003800523","first-page":"333","volume-title":"Emergency Medicine: a Comprehensive Study Guide","author":"Green BG","year":"2004","edition":"6"},{"key":"bibr10-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712043372310"},{"key":"bibr11-147323001003800523","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-106-2-181"},{"key":"bibr12-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0644(05)82515-6"},{"key":"bibr13-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198505023121801"},{"key":"bibr14-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(89)90857-6"},{"key":"bibr15-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198405173102001"},{"key":"bibr16-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/102.6.802"},{"key":"bibr17-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/91.1.82"},{"key":"bibr18-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92158-X"},{"key":"bibr19-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198711263172201"},{"key":"bibr20-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.75.6.1170"},{"key":"bibr21-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.17.4.628"},{"key":"bibr22-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(99)80042-3"},{"key":"bibr23-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.219.25"},{"key":"bibr24-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01023-8"},{"key":"bibr25-147323001003800523","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.21.6.1059"}],"container-title":["Journal of International Medical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323001003800523","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/147323001003800523","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:43:26Z","timestamp":1777459406000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/147323001003800523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["10.1177\/147323001003800523"],"URL":"https:\/\/doi.org\/10.1177\/147323001003800523","relation":{},"ISSN":["0300-0605","1473-2300"],"issn-type":[{"value":"0300-0605","type":"print"},{"value":"1473-2300","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10]]}}}