{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:57:19Z","timestamp":1789520239853,"version":"build-2803163510"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Cardiovascular Nursing"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:sec><jats:title>Background and purpose:<\/jats:title><jats:p> Among members of the health care team, nurses play a large role in actively engaging stroke survivors in secondary stroke prevention programs. This systematic review and meta-analysis examines the effectiveness of interventions in which nurses have a primary role on modification of risk factors among stroke survivors. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> We systematically searched for randomized controlled trials in relevant databases investigating the role of nurses in secondary stroke prevention. Meta-analyses were conducted using Cochrane Review Manager Software. The mean pooled effect size, a 95% confidence interval (CI), and I-squared ( I<jats:sup>2<\/jats:sup>) for heterogeneity were calculated. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Sixteen randomized controlled trials were included with a total of 3568 stroke and transient ischemic attack patients. After removing one outlier, the models demonstrated a statistically significant effect on reducing systolic blood pressure (SMD = \u22120.14 (95% CI = \u22120.23, \u20130.05), I<jats:sup>2<\/jats:sup> = 0%; p = 0.002, six studies, n =1885) and diastolic blood pressure (SMD = \u22120.16 (95% CI = \u22120.27, \u20130.05), I<jats:sup>2<\/jats:sup> = 0%; p = 0.003, four studies, n =1316). The interventions also significantly improved physical activity (five studies, n=1234), diet (three studies, n=425), medication adherence (two studies, n=270), and knowledge of risk factors (three studies, n=516). However, there was no effect on smoking cessation or reduction in use of alcohol. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> We found that interventions in which nurses had a primary role were effective on improving medical and behavioral risk factors, as well as knowledge of risk factors as part of secondary prevention of stroke. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1474515118779732","type":"journal-article","created":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T13:05:53Z","timestamp":1527858353000},"page":"728-736","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Effectiveness of interventions involving nurses in secondary stroke prevention: A systematic review and meta-analysis"],"prefix":"10.1093","volume":"17","author":[{"given":"Beena P","family":"Parappilly","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Rehabilitation Research Program, GF Strong Rehabilitation Research Lab., Vancouver Coastal Health Research Institute, Canada"},{"name":"Stroke Unit, Medicine Program, St. Paul\u2019s Hospital, Providence Health Care, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thalia S","family":"Field","sequence":"additional","affiliation":[{"name":"Vancouver Stroke Program, Division of Neurology, Faculty of Medicine, University of British Columbia, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William B","family":"Mortenson","sequence":"additional","affiliation":[{"name":"Rehabilitation Research Program, GF Strong Rehabilitation Research Lab., Vancouver Coastal Health Research Institute, Canada"},{"name":"Department of Occupational Science and Occupational Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"International Collaboration on Repair Discoveries, Vancouver, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brodie M","family":"Sakakibara","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Rehabilitation Research Program, GF Strong Rehabilitation Research Lab., Vancouver Coastal Health Research Institute, Canada"},{"name":"Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janice J","family":"Eng","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, Canada"},{"name":"Rehabilitation Research Program, GF Strong Rehabilitation Research Lab., Vancouver Coastal Health Research Institute, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,6,1]]},"reference":[{"key":"bibr1-1474515118779732","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000201253.93811.f6"},{"key":"bibr2-1474515118779732","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60834-3"},{"key":"bibr3-1474515118779732","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000024"},{"key":"bibr4-1474515118779732","author":"Wein T","year":"2017","journal-title":"Int J Stroke"},{"key":"bibr6-1474515118779732","volume-title":"Strategies to support self-management in chronic conditions: Collaboration with clients","author":"Registered Nurses\u2019 Association of Ontario"},{"key":"bibr7-1474515118779732","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5402.177"},{"key":"bibr8-1474515118779732","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.38"},{"key":"bibr11-1474515118779732","unstructured":"Review Manager. 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