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Across four studies (total N = 1,849), we used both experimental (pathogen priming) and individual differences (pathogen disgust sensitivity [PDS]) approaches to test whether the behavioral immune system influences prejudice toward immigrants indiscriminately (the generalized out-group prejudice hypothesis) or specifically toward immigrants from a pathogen-rich ecology (the origin-specific out-group prejudice hypothesis). Internal meta-analyses lend some support to both hypotheses. At the experimental level, pathogen primes had no effect on attitudes toward origin-unspecified immigrants or immigrants from a pathogen-rich ecology. At the individual differences level, PDS has a unique negative effect on comfort with immigrants from pathogen-rich ecologies but not on comfort with immigrants from unspecified ecologies. However, pathogen disgust sensitivity was negatively related to the decision to allow entry to both origin-unspecified immigrants and immigrants from a pathogen-rich ecology.<\/jats:p>","DOI":"10.1177\/1474704919826851","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T01:26:44Z","timestamp":1549848404000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":55,"title":["Generalized or Origin-Specific Out-Group Prejudice?: The Role of Temporary and Chronic Pathogen-Avoidance Motivation in Intergroup Relations"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6372-4845","authenticated-orcid":false,"given":"Tingting","family":"Ji","sequence":"first","affiliation":[{"name":"Department of Experimental and Applied Psychology, Institute of Brain and Behavior Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua M.","family":"Tybur","sequence":"additional","affiliation":[{"name":"Department of Experimental and Applied Psychology, Institute of Brain and Behavior Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"van Vugt","sequence":"additional","affiliation":[{"name":"Department of Experimental and Applied Psychology, Institute of Brain and Behavior Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,2,10]]},"reference":[{"key":"bibr1-1474704919826851","doi-asserted-by":"publisher","DOI":"10.1017\/S0003055416000770"},{"key":"bibr2-1474704919826851","volume-title":"Multiple regression: Testing and interpreting interactions","author":"Aiken L. 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