{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:23:27Z","timestamp":1777940607442,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Royal College of Physicians of Edinburgh"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Stenotrophomonas maltophilia causes opportunistic respiratory infections and is associated with declining lung function in patients with cystic fibrosis (CF). Risk factors for carrying S. maltophilia remain unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We conducted a retrospective study of patients yielding \u2a7e1 respiratory S. maltophilia isolate at the Oxford University Hospitals Trust between 2014 and 2019 and a cohort study of S. maltophilia carriage in CF patients attending annual review in 2018.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Seven hundred and forty isolates were identified from 238 patients (median 1.0 isolate\/patient). Predisposing conditions included invasive ventilation (29.8%), CF (25.6%) and non-CF bronchiectasis (24.4%). The rates of Stenotrophomonas isolates and co-trimoxazole resistance were stable over time. About 10.8% of isolates were co-trimoxazole-resistant, with resistance more common in CF than in other diagnoses (29.5% vs 5.8%, p\u2009&lt;\u20090.001). No clinical features were significantly associated with S. maltophilia carriage in the CF population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>We present new insight into the epidemiology of Stenotrophomonas colonisation\/infection and identify increased co-trimoxazole resistance in CF isolates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14782715221088909","type":"journal-article","created":{"date-parts":[[2022,6,16]],"date-time":"2022-06-16T10:09:15Z","timestamp":1655374155000},"page":"14-19","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical associations with carriage of pulmonary\n                    <i>Stenotrophomonas maltophilia<\/i>"],"prefix":"10.1177","volume":"52","author":[{"given":"Lily","family":"Watson","sequence":"first","affiliation":[{"name":"Oxford University, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Priestley","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J","family":"Chapman","sequence":"additional","affiliation":[{"name":"Oxford University \u2013 Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique I","family":"Andersson","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William G","family":"Flight","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Foundation Trust, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,6,9]]},"reference":[{"key":"bibr1-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00019-11"},{"key":"bibr2-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2019.08.006"},{"key":"bibr3-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23781"},{"key":"bibr4-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23217"},{"key":"bibr5-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201009-1392OC"},{"key":"bibr6-14782715221088909","volume":"6","author":"Gajdacs M","year":"2019","journal-title":"Health Serv Res Manag Epidemiol"},{"key":"bibr7-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1007\/BF01690098"},{"key":"bibr8-14782715221088909","volume":"41","author":"Alonso A","year":"1997","journal-title":"Stenotrophomonas maltophilia. Antimicrob Agents Chemother"},{"key":"bibr9-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2014.06.005"},{"key":"bibr10-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2014.864553"},{"key":"bibr11-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(02)00141-8"},{"key":"bibr12-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00100805"},{"key":"bibr13-14782715221088909","unstructured":"Standards Unit, Microbiology Services, PHE. UK Standards for Microbiology Investigations. Investigation of Bronchoalveolar Lavage, Sputum and Associated Specimens. B57. London: PHE; 2019."},{"key":"bibr14-14782715221088909","unstructured":"The European Committee on Antimicrobial Susceptibility Testing [Internet]. Breakpoint tables for interpretation of MICs and zone diameters, version 11.0, https:\/\/www.eucast.org\/fileadmin\/src\/media\/PDFs\/EUCAST_files\/Breakpoint_tables\/v_11.0_Breakpoint_Tables.pdf (2021, accessed 19 January 2022)."},{"key":"bibr15-14782715221088909","first-page":"2","volume":"8","author":"Chawla K","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"bibr16-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000019250"},{"key":"bibr17-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1053\/jhin.2001.1099"},{"key":"bibr18-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2018.10.011"},{"key":"bibr19-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10216"},{"key":"bibr20-14782715221088909","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9010015"},{"key":"bibr21-14782715221088909","volume":"3","author":"Amin R","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr22-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0496(200007)30:1<10::AID-PPUL3>3.0.CO;2-Q"},{"key":"bibr23-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23943"},{"key":"bibr24-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00007203"},{"key":"bibr25-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2013.05.009"},{"key":"bibr26-14782715221088909","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00855-19"}],"container-title":["Journal of the Royal College of Physicians of Edinburgh"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14782715221088909","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/14782715221088909","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14782715221088909","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T05:55:14Z","timestamp":1777701314000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/14782715221088909"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1177\/14782715221088909"],"URL":"https:\/\/doi.org\/10.1177\/14782715221088909","relation":{},"ISSN":["1478-2715","2042-8189"],"issn-type":[{"value":"1478-2715","type":"print"},{"value":"2042-8189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3]]}}}