{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:24:13Z","timestamp":1777940653757,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T00:00:00Z","timestamp":1702252800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Journal of the Royal College of Physicians of Edinburgh"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>Hypothyroidism is an endocrine disorder which occurs due to a deficiency of thyroid hormones. Hoffmann\u2019s syndrome is a rare complication of hypothyroidism \u2013 presenting as hypothyroid myopathy. We describe the case of a 20-year-old lactating female, known to have hypothyroidism (diagnosed during her pregnancy and having discontinued treatment following delivery), presenting with complaints of pain, swelling of bilateral calf muscles with cramps in bilateral lower limbs. Symptoms of muscle pseudohypertrophy with muscle stiffness are relatively rare in subclinical hypothyroidism and it is important to identify and diagnose this rare condition, and initiate appropriate treatment.<\/jats:p>","DOI":"10.1177\/14782715231218033","type":"journal-article","created":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T06:44:44Z","timestamp":1702277084000},"page":"26-28","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Hoffmann\u2019s syndrome in subclinical hypothyroidism"],"prefix":"10.1177","volume":"54","author":[{"given":"Kiran","family":"HS","sequence":"first","affiliation":[{"name":"Department of General Medicine, JSS Medical College and Hospital, Mysuru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashank","family":"Cheemalapati","sequence":"additional","affiliation":[{"name":"Department of General Medicine, JSS Medical College and Hospital, Mysuru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkatesh","family":"CR","sequence":"additional","affiliation":[{"name":"Department of General Medicine, JSS Medical College and Hospital, Mysuru, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,12,11]]},"reference":[{"key":"bibr1-14782715231218033","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.113755"},{"key":"bibr2-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1998.8.1033"},{"key":"bibr3-14782715231218033","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.904691"},{"key":"bibr4-14782715231218033","volume":"102","author":"Deepak S","year":"2004","journal-title":"J Indian Med Assoc"},{"key":"bibr5-14782715231218033","volume":"51","author":"Udayakumar N","year":"2005","journal-title":"J Postgrad Med"},{"key":"bibr6-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880131011"},{"key":"bibr7-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70186-9"},{"key":"bibr8-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-016-9357-0"},{"key":"bibr9-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(05)70176-6"},{"key":"bibr10-14782715231218033","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.109672"},{"key":"bibr11-14782715231218033","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.22123"},{"key":"bibr12-14782715231218033","volume":"3","author":"Qureshi W","year":"2005","journal-title":"Ger Med Sci"},{"key":"bibr13-14782715231218033","unstructured":"Werner SC, Ingbar SH, Braverman LE, et al. Werner and Ingbar\u2019s the thyroid: a fundamental and clinical text. 9th ed. Philadelphia: Lippincott Williams and Wilkins; 2005. p. 894\u20135."}],"container-title":["Journal of the Royal College of Physicians of Edinburgh"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14782715231218033","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/14782715231218033","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14782715231218033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T05:56:46Z","timestamp":1777701406000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/14782715231218033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,11]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1177\/14782715231218033"],"URL":"https:\/\/doi.org\/10.1177\/14782715231218033","relation":{},"ISSN":["1478-2715","2042-8189"],"issn-type":[{"value":"1478-2715","type":"print"},{"value":"2042-8189","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,11]]}}}