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When thalidomide was tested against placebo by the trialist Louis Lasagna in 1960 (while the drug was banned from the U.S. marketplace), he found the 100-mg dosage equivalent to placebo, as well as greatly inferior to the 200-mg dosage, in producing sleep. Even as these findings were made known, a 100-mg dose of thalidomide was in general use as a sleep aid for pregnant women. It appears that unbeknownst to themselves, an untold number of pregnant women around the world who were prescribed thalidomide incurred the risks of a teratogen in return for the benefits of a sugar pill.<\/jats:p>","DOI":"10.1177\/14782715241258503","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T01:21:36Z","timestamp":1716945696000},"page":"161-164","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Was thalidomide a placebo hypnotic?"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0590-6595","authenticated-orcid":false,"given":"Stewart","family":"Justman","sequence":"first","affiliation":[{"name":"College of Humanities and Sciences, University of Montana, Missoula, MT, 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