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On evaluation, she was found to have elevated acetylcholine receptor antibody levels and a positive neostigmine test confirming the diagnosis of ocular myasthenia gravis (MG). The patient was treated with oral prednisolone and pyridostigmine resulting in significant improvement within 2\u2009weeks. The co-occurrence of systemic sclerosis (SSc) and MG is rare and when such an association is seen, it is usually seen in the background of D-Penicillamine therapy for SSc. The presence of fluctuating ptosis in SSc is a valuable clinical clue to suspect co-existence of neuromuscular junction disorder like MG.<\/jats:p>","DOI":"10.1177\/14782715251362060","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T04:41:47Z","timestamp":1754023307000},"page":"188-192","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Overlap of limited cutaneous systemic sclerosis with ocular myasthenia gravis- report of a case and a brief review of literature"],"prefix":"10.1177","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5313-7316","authenticated-orcid":false,"given":"Harikrishnan","family":"Gangadharan","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Government Medical College Kottayam, Kottayam, KL, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6670-0661","authenticated-orcid":false,"given":"Sandra Pulickal","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Government Medical College Kottayam, Kottayam, KL, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8476-3007","authenticated-orcid":false,"given":"Rohit Ram","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Neurology, Government Medical College Kottayam, Kottayam, KL, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aditya","family":"Nair","sequence":"additional","affiliation":[{"name":"Department of Neurology, Christian Medical College, Vellore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjit","family":"PS","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Government Medical College Kottayam, Kottayam, KL, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"George","sequence":"additional","affiliation":[{"name":"Department of Neurology, Government Medical College Kottayam, Kottayam, KL, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0806188"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-104-5-699"},{"issue":"4","key":"e_1_3_3_4_2","article-title":"D-penicillamine induced myasthenia gravis: clinical, serological and genetic findings","volume":"11","author":"Drosos AA","year":"1993","unstructured":"Drosos AA, Christou L, Galanopoulou V, Tzioufas AG, Tsiakou EK. 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