{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:13:06Z","timestamp":1777558386984,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,12,18]],"date-time":"2014-12-18T00:00:00Z","timestamp":1418860800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:p>We aimed to study whether pulse pressure (PP) predicts the response of diabetic nephropathy to glucose-lowering treatment. Patients with uncontrolled type 2 diabetes were followed for decrease in albuminuria after insulin\/oral-hypoglycemic treatment. A total of 143 patients were followed for a median time of 10.5 months in a cohort study. Fasting blood sugar and HbA1C significantly decreased, while systolic, diastolic and pulse pressures remained constant during intervention. Median albuminuria decreased from 18.4 mg\/day [10\u201340] to 16.4 mg\/day [9\u201328] at the end of study (p-value &lt; 0.005). The number of patients with normo\/micro\/macro-albuminuria changed from 98\/36\/9 to 108\/31\/4 (p-value &lt; 0.001). No significant difference in baseline PP (47.5 \u00b11.61 vs. 45.9 \u00b11.81 mmHg; p-value = 0.51) or final PP (47.0 \u00b12.41 vs. 49.4 \u00b12.38 mmHg; p-value = 0.47) existed between those with decreased and increased albuminuria. PP was not a significant predictor of albuminuria changes in receiver operating characteristic curve (p-value = 0.77) and regression (p-value = 0.98) analyses. Benefits of glycemic control in diabetic nephropathy are independent of PP.<\/jats:p>","DOI":"10.1177\/1479164114559208","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T05:30:37Z","timestamp":1418967037000},"page":"150-151","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pulse pressure does not predict the response of diabetic nephropathy to glucose-lowering therapy"],"prefix":"10.1177","volume":"12","author":[{"given":"Manouchehr","family":"Nakhjavani","sequence":"first","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arash Aghajani","family":"Nargesi","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Behnam","family":"Heidari","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaniar","family":"Ghazizadeh","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehrdad","family":"Larry","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza","family":"Esteghamati","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,12,18]]},"reference":[{"key":"bibr1-1479164114559208","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.4.421"},{"key":"bibr2-1479164114559208","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8227(00)00155-8"},{"key":"bibr3-1479164114559208","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.35.1.48"},{"key":"bibr4-1479164114559208","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000232644.98208.65"},{"key":"bibr5-1479164114559208","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.2007.S5"},{"key":"bibr6-1479164114559208","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.177469"}],"container-title":["Diabetes and Vascular Disease Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1479164114559208","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1479164114559208","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1479164114559208","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:22:27Z","timestamp":1777400547000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1479164114559208"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,18]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1177\/1479164114559208"],"URL":"https:\/\/doi.org\/10.1177\/1479164114559208","relation":{},"ISSN":["1479-1641","1752-8984"],"issn-type":[{"value":"1479-1641","type":"print"},{"value":"1752-8984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,18]]}}}