{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:06:11Z","timestamp":1777557971563,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T00:00:00Z","timestamp":1510099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The combined effect of vitamin D and parathyroid hormone on glucose homeostasis has not been adequately investigated. The aim of this study was to examine the role of parathyroid hormone\/vitamin D axis on glucose homeostasis in elderly persons with prediabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Patients with prediabetes ( n\u2009=\u2009144) and healthy age-matched controls ( n\u2009=\u200981) were included in this cross-sectional study. Study parameters included anthropometric characteristics, morning fasting glucose (fasting plasma glucose), insulin (fasting plasma insulin), parathyroid hormone, 25-hydroxyvitamin D, homeostasis model assessment of insulin resistance and homeostasis model assessment of \u03b2-cell function. Both groups were stratified into subgroups according to vitamin D status and tertiles of parathyroid hormone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Both groups were comparable in terms of body mass index, 25-hydroxyvitamin D and parathyroid hormone status. In the prediabetes group, fasting plasma glucose differed significantly across parathyroid hormone tertiles, increasing from the first to the third tertile ( p\u2009=\u20090.011). There were higher fasting plasma glucose values in participants with vitamin D deficiency\/parathyroid hormone third tertile compared to all other groups ( p\u2009=\u20090.031, 0.027 and 0.039, respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Parathyroid hormone status is associated with impaired glucose homeostasis; hypovitaminosis D combined with high parathyroid hormone concentrations are associated with glycaemic dysregulation in elderly patients with prediabetes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1479164117738443","type":"journal-article","created":{"date-parts":[[2017,11,8]],"date-time":"2017-11-08T04:51:51Z","timestamp":1510116711000},"page":"150-153","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["The combined effect of vitamin D and parathyroid hormone concentrations on glucose homeostasis in older patients with prediabetes: A cross-sectional study"],"prefix":"10.1177","volume":"15","author":[{"given":"Spyridon N","family":"Karras","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panagiotis","family":"Anagnostis","sequence":"additional","affiliation":[{"name":"Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Antonopoulou","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xanthippi","family":"Tsekmekidou","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theocharis","family":"Koufakis","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios G","family":"Goulis","sequence":"additional","affiliation":[{"name":"Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pantelis","family":"Zebekakis","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalliopi","family":"Kotsa","sequence":"additional","affiliation":[{"name":"Division of Endocrinology and Metabolism and Diabetes Center, First Department of Internal Medicine, School of Medicine, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,11,8]]},"reference":[{"key":"bibr1-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.12.053"},{"key":"bibr2-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-016-9403-y"},{"key":"bibr3-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-16-0391"},{"key":"bibr4-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2011.111"},{"key":"bibr5-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1089\/met.2012.0056"},{"key":"bibr6-1479164117738443","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-S005"},{"key":"bibr7-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1007\/BF00280883"},{"key":"bibr8-1479164117738443","unstructured":"Ross AC, Taylor CL, Yaktine AL, et al. (eds) Dietary reference intakes for calcium and vitamin D. Washington, DC: The National Academies Press, 2011, p. 98."},{"key":"bibr9-1479164117738443","first-page":"E975","volume":"258","author":"Fadda GZ","year":"1990","journal-title":"Am J Physiol"},{"key":"bibr10-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2015.12.012"},{"key":"bibr11-1479164117738443","doi-asserted-by":"publisher","DOI":"10.1111\/dme.12893"}],"container-title":["Diabetes and Vascular Disease Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1479164117738443","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1479164117738443","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1479164117738443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:20:24Z","timestamp":1777400424000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1479164117738443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,8]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1177\/1479164117738443"],"URL":"https:\/\/doi.org\/10.1177\/1479164117738443","relation":{},"ISSN":["1479-1641","1752-8984"],"issn-type":[{"value":"1479-1641","type":"print"},{"value":"1752-8984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,8]]}}}