{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:06:18Z","timestamp":1777557978859,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T00:00:00Z","timestamp":1511913600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We assessed the association between admission blood glucose levels and acute stroke mortality and examined whether there was any incremental value of adding glucose status to the validated acute stroke mortality predictor \u2013 the SOAR (stroke subtype, Oxford Community Stroke Project classification, age, and pre-stroke modified Rankin) score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Data from Norfolk and Norwich University Hospital stroke and Transient Ischaemic Attack register (2003\u20132013) and Anglia Stroke Clinical Network Evaluation Study (2009\u20132012) were analysed. Multivariable logistic regression analysis assessed the association between admission blood glucose levels with inpatient and 7-day mortality. The prognostic ability of the SOAR score was then compared with the SOAR with glucose score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 5575 acute stroke patients (ischaemic stroke: 89.2%) with mean age (standard deviation) of 76.97 (\u2009\u00b1\u200911.88\u2009) years were included. Both borderline hyperglycaemia (7.9\u201311.0\u2009mmol\/L) and hyperglycaemia (&gt;11.0\u2009mmol\/L) when compared to normoglycaemia (4.0\u20137.8\u2009mmol\/L) were associated with both 7-day and inpatient mortality after controlling for sex, age, Oxford Community Stroke Project classification and pre-stroke modified Rankin score. Both the SOAR stroke score and SOAR-G score were good predictors of inpatient stroke mortality [area under the curve: 0.82 (95% confidence interval: 0.81\u20130.84) and 0.83 (95% confidence interval: 0.81\u20130.84)], respectively. These scores were also good at predicting outcomes in both patients with and without diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>High blood glucose levels at admission were associated with worse acute stroke mortality outcomes. The constituents of the SOAR stroke score were good at predicting mortality after stroke.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1479164117743034","type":"journal-article","created":{"date-parts":[[2017,11,29]],"date-time":"2017-11-29T08:18:16Z","timestamp":1511943496000},"page":"114-121","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Hyperglycaemia and the SOAR stroke score in predicting mortality"],"prefix":"10.1177","volume":"15","author":[{"given":"Stephen J","family":"McCall","sequence":"first","affiliation":[{"name":"Ageing Clinical and Experimental Research Group, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK"},{"name":"Nuffield Department of Population Health, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turkiah A","family":"Alanazi","sequence":"additional","affiliation":[{"name":"Ageing Clinical and Experimental Research Group, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan B","family":"Clark","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley D","family":"Musgrave","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joao H","family":"Bettencourt-Silva","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max O","family":"Bachmann","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony K","family":"Metcalf","sequence":"additional","affiliation":[{"name":"Norfolk and Norwich University Hospital, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristian M","family":"Bowles","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"},{"name":"Norfolk and Norwich University Hospital, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamas A","family":"Mamas","sequence":"additional","affiliation":[{"name":"Keele Cardiovascular Research Group, Centre for Prognosis Research Institute of Primary Care and Health Sciences, Keele University, Stoke-on-Trent, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John F","family":"Potter","sequence":"additional","affiliation":[{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"},{"name":"Norfolk and Norwich University Hospital, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Phyo K","family":"Myint","sequence":"additional","affiliation":[{"name":"Ageing Clinical and Experimental Research Group, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK"},{"name":"Norwich Medical School, University of East Anglia, Norwich, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,11,29]]},"reference":[{"key":"bibr1-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70080-7"},{"key":"bibr2-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1007\/BF00812155"},{"key":"bibr3-1479164117743034","doi-asserted-by":"publisher","DOI":"10.2174\/156802609789869600"},{"key":"bibr4-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.932822"},{"key":"bibr5-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.983353"},{"key":"bibr6-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001148"},{"key":"bibr7-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000078657.22835.B9"},{"key":"bibr8-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1111\/ijs.12088"},{"key":"bibr9-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12577"},{"key":"bibr10-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/aft075"},{"key":"bibr11-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-301076"},{"key":"bibr12-1479164117743034","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2009.02526.x"},{"key":"bibr13-1479164117743034","first-page":"342","volume":"7","author":"Kwok 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