{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T21:42:35Z","timestamp":1791754955895,"version":"4.3.4"},"reference-count":32,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003669","name":"korea centers for disease control and prevention","doi-asserted-by":"publisher","award":["2016-ER6304-02"],"award-info":[{"award-number":["2016-ER6304-02"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>We compared the 2-year clinical outcomes between prediabetes and type 2 diabetes mellitus (T2DM) according to the pre-percutaneous coronary intervention (PCI) thrombolysis in myocardial infarction (TIMI) flow grade in patients with ST-segment elevation myocardial infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Overall, 6448 STEMI patients were divided into two groups: pre-PCI TIMI 0\/1 group ( n\u2009=\u20094854) and pre-PCI TIMI 2\/3 group ( n\u2009=\u20091594). They were further divided into patients with normoglycemia, prediabetes, and T2DM. The major endpoint was major adverse cardiac events (MACEs), defined as all-cause death, recurrent myocardial infarction, or any repeat revascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In the pre-PCI TIMI 0\/1 group, all-cause death rate was higher in both prediabetes (adjusted hazard ratio [aHR]: 1.633, p\u2009=\u20090.045) and T2DM (aHR: 2.064, p\u2009=\u20090.002) groups than in the normoglycemia group. In the pre-PCI TIMI 2\/3 group, any repeat revascularization rate was also higher in both prediabetes (aHR: 2.511, p\u2009=\u20090.039) and T2DM (aHR: 3.156, p\u2009=\u20090.009) than normoglycemia. In each group (pre-PCI TIMI 0\/1 or 2\/3), the MACEs and all other clinical outcomes rates were similar between the prediabetes and T2DM groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Prediabetes showed comparable worse clinical outcomes to those of T2DM regardless of the pre-PCI TIMI flow grade.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1479164121991505","type":"journal-article","created":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T00:26:14Z","timestamp":1612830374000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Prediabetes versus type 2 diabetes mellitus based on pre-percutaneous coronary intervention thrombolysis in myocardial infarction flow grade in patients with ST-segment elevation myocardial infarction after successful newer-generation drug-eluting stent implantation"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9669-3598","authenticated-orcid":false,"given":"Yong Hoon","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ae-Young","family":"Her","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiovascular Center, Chonnam National University Hospital, Gwangju, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeong-Keuk","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Jin","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2641-9606","authenticated-orcid":false,"given":"Seunghwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul-Min","family":"Ahn","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Guk","family":"Ko","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghoon","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Severance Cardiovascular Hospital, Yonsei 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Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,3]]},"reference":[{"key":"bibr1-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1161\/hc3101.093701"},{"key":"bibr2-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2017.04.004"},{"key":"bibr3-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.115.002365"},{"key":"bibr4-1479164121991505","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-2462"},{"key":"bibr5-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5953"},{"key":"bibr6-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.10.038"},{"key":"bibr7-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2019.107994"},{"key":"bibr8-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-16-0061"},{"key":"bibr9-1479164121991505","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-2856"},{"key":"bibr10-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.326.7399.1137"},{"key":"bibr11-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.822791"},{"key":"bibr12-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1177\/0003319712474113"},{"key":"bibr13-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182742c84"},{"key":"bibr14-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"},{"key":"bibr15-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198504043121437"},{"key":"bibr16-1479164121991505","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-S011"},{"key":"bibr17-1479164121991505","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-17-01067"},{"key":"bibr18-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28440"},{"key":"bibr19-1479164121991505","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2018.11.030"},{"key":"bibr20-1479164121991505","volume-title":"TIMI 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