{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T16:23:19Z","timestamp":1792167799363,"version":"4.4.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Insulin Resistance (IR) are associated with Hypertension (HTN). Triglyceride glucose-body mass index (TyG-BMI) is a readily available and clinically significant indicator of IR. This study aimed to investigate whether TyG-BMI is independently associated with HTN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 15,464 patients with normal blood glucose from 2004 to 2016 participated in this study. Participants were divided into four groups using the quartile method: TyG-BMI below 153.1, between 153.1 and 174.2, between 174.2 and 199.3, and over 199.3. The covariates included age, sex, BMI, WC, HDL-C, TC, TG, HbA1c, FPG, ALT, AST, GGT, SBP, DBP, smoking status, alcohol consumption, and exercise habits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The average age was 43.7 \u00b1 8.9\u00a0years, and 45.4% were men. The prevalence of HTN was 6.2% (964\/15464) of the population. TyG-BMI remained significantly associated with HTN after multivariate adjustment for TyG-BMI as a continuous variable (adjusted OR = 2.87, 95% CI: 1.90\u20134.34). Each 10-unit rise in TyG-BMI (continuous variable) was linked to a 31% increase in the prevalence of HTN (adjusted OR = 1.31, 95% CI: 1.25\u20131.37). In the subgroup analysis stratified by age, sex, waist circumference, and smoking status, the association between TyG-BMI and HTN were stable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this study, TyG-BMI was highly correlated with HTN, but more experiments and different populations are needed to verify this.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14791641231173617","type":"journal-article","created":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T05:57:47Z","timestamp":1684562267000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":50,"title":["TyG-BMI and hypertension in Normoglycemia subjects in Japan: A cross-sectional study"],"prefix":"10.1177","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1293-7290","authenticated-orcid":false,"given":"Xinming","family":"Huang","sequence":"first","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiacheng","family":"He","sequence":"additional","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoxin","family":"Wu","sequence":"additional","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zishu","family":"Peng","sequence":"additional","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yang","sequence":"additional","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Langxi","family":"Ye","sequence":"additional","affiliation":[{"name":"Nanhai District People\u2019s Hospital of Foshan, Foshan City, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,20]]},"reference":[{"key":"bibr1-14791641231173617","volume-title":"Guideline for the pharmacological treatment of hypertension in adults","year":"2021"},{"key":"bibr2-14791641231173617","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000002453"},{"issue":"4","key":"bibr3-14791641231173617","first-page":"24","volume":"51","author":"Romero FdL","year":"1998","journal-title":"Rev. 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