{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T02:42:23Z","timestamp":1778812943683,"version":"3.51.4"},"reference-count":49,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The Major Research Project of Scientific and Technological Innovation Project of Chinese Academy of Chinese Medicine Sciences","award":["CI2021A00913"],"award-info":[{"award-number":["CI2021A00913"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81973686"],"award-info":[{"award-number":["81973686"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes and Vascular Disease Research"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The intricate interaction between oxidative stress and atherosclerotic cardiovascular disease (ASCVD) is an essential area of research because of the potential role of oxidative homeostasis in regulating ASCVD risk. This study aimed to investigate the relationship between the oxidative balance score (OBS) and the 10-years risk of ASCVD to gain insight into how oxidative balance affects cardiovascular health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study analyzed National Health and Nutrition Examination Survey (NHANES) 2011\u20132020 data (40\u201379 age group), exploring OBS\u2019s link to 10-years ASCVD risk. OBS categorized dietary and lifestyle factors. Multivariate logistic regression controlled for age, sex, race, and demographics. A restricted cubic spline examined linear relationships; robustness was ensured through subgroup analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Analysis of 4955 participants reveals a negative association between OBS and 10-years ASCVD risk. Continuous OBS adjusted OR: 0.97 (95% CI: 0.95\u223c0.99, p &lt; .001). Quartile analysis shows reduced risk in Q2 0.88 (95% CI: 0.63\u223c1.22, p = .43), Q3 0.92 (95% CI: 0.66\u223c1.28, p = .614), and Q4 0.59 (95% CI: 0.42\u223c0.83, p = .002) compare Q1. Quartile analysis indicated decreasing risk in higher OBS quartiles. Lifestyle OBS and Dietary OBS demonstrated similar trends. Stratified analyses highlight race and hypertension as effect modifiers ( p &lt; .05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our study suggests an association between higher OBS and a reduced 10-years ASCVD risk. However, causation should not be inferred, and in the future, more extensive clinical and fundamental research is required to delve deeper into this association.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14791641241244658","type":"journal-article","created":{"date-parts":[[2024,4,10]],"date-time":"2024-04-10T08:27:20Z","timestamp":1712737640000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["A cross-sectional study exploring the relationship between oxidative balance score and 10-year atherosclerotic cardiovascular disease risk based on the National Health and Nutrition Examination Survey (2011\u20132020)"],"prefix":"10.1177","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0198-6329","authenticated-orcid":false,"given":"Rumeng","family":"Wang","sequence":"first","affiliation":[{"name":"National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei","family":"Xue","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China"},{"name":"Department of cardiology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,10]]},"reference":[{"issue":"23","key":"bibr1-14791641241244658","doi-asserted-by":"crossref","first-page":"e674","DOI":"10.1161\/CIR.0000000000000395","volume":"133","author":"Sacco RL","year":"2016","journal-title":"Circulation"},{"issue":"1","key":"bibr2-14791641241244658","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/ehjcvp\/pvad074","volume":"10","author":"Zheng WC","year":"2023","journal-title":"Eur Heart J Cardiovasc 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