{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:12:30Z","timestamp":1789881150268,"version":"4.0.1"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2015,12,23]],"date-time":"2015-12-23T00:00:00Z","timestamp":1450828800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p>The aim was to undertake a cost-utility analysis of a self-management programme of activity, coping and education (SPACE) for chronic obstructive pulmonary disease (COPD). The analysis was conducted alongside a six-month randomized controlled trial in 30 primary care settings. The economic analysis used data from 184 patients with confirmed diagnosis of COPD, forced expiratory volume in one second\/forced vital capacity ratio &lt;0.7 and with grade 2\u20135 on the Medical Research Council dyspnoea scale. Participants received either a self-management programme consisting of an education manual (SPACE for COPD) and consultation or usual care. Six-month costs were estimated from the National Health Service and Personal Social Services perspective and quality-adjusted life years (QALYs) were calculated based on patient responses at baseline and six months.<\/jats:p>\n                  <jats:p>The mean difference in costs between usual care and SPACE FOR COPD programme was \u2212\u00a327.18 (95% confidence interval (CI); \u2212\u00a3122.59 to \u00a368.25) while mean difference in QALYs was \u22120.10 (95% CI; \u22120.17 to \u22120.02). The results suggest that the intervention is more costly and more effective than usual care. The probability of the intervention being cost-effective was 97% at a threshold of \u00a320,000\/QALY gained. We conclude that the SPACE FOR COPD programme is cost-effective compared to usual care.<\/jats:p>","DOI":"10.1177\/1479972315619578","type":"journal-article","created":{"date-parts":[[2015,12,24]],"date-time":"2015-12-24T20:24:03Z","timestamp":1450988643000},"page":"48-56","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["An economic evaluation of a self-management programme of activity, coping and education for patients with chronic obstructive pulmonary disease"],"prefix":"10.1177","volume":"13","author":[{"given":"Melina","family":"Dritsaki","sequence":"first","affiliation":[{"name":"Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki","family":"Johnson-Warrington","sequence":"additional","affiliation":[{"name":"Centre for Exercise and Rehabilitation Science, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Centre for Exercise and Rehabilitation Science, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sally","family":"Singh","sequence":"additional","affiliation":[{"name":"Centre for Exercise and Rehabilitation Science, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Rees","sequence":"additional","affiliation":[{"name":"Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,12,23]]},"reference":[{"key":"bibr1-1479972315619578","unstructured":"The World Health Organisation. 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