{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:53:35Z","timestamp":1777532015521,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:p>The effect of early rehabilitation on the outcome of patients with chronic obstructive pulmonary disease (COPD) and acute respiratory failure (ARF) in intensive care units (ICUs) remains unclear. We examined the effect of early rehabilitation on the outcomes of COPD patients requiring mechanical ventilation (MV) in the ICU. This retrospective, observational, case\u2013control study was conducted in a medical center with a 19-bed ICU. The records of all 105 ICU patients with COPD and ARF who required MV from January to December 2011 were examined. The outcomes (MV duration, rates of successful weaning and survival, lengths of ICU and hospital stays, and medical costs) were recorded and analyzed. During the study period, 35 patients with COPD underwent early rehabilitation in the ICU and 70 demographically and clinically matched patients with similar COPD stage, cause of intubation, type of respiratory failure, and levels of disease severity who had not undergone early rehabilitation in the ICU were selected as comparative controls. Multiple regression analysis showed that early rehabilitation was significantly negatively associated with MV duration. Early rehabilitation for COPD patients in the ICU with ARF shortened the duration of their MV.<\/jats:p>","DOI":"10.1177\/1479973118820310","type":"journal-article","created":{"date-parts":[[2019,1,4]],"date-time":"2019-01-04T01:18:06Z","timestamp":1546564686000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Effectiveness of early rehabilitation on patients with chronic obstructive lung disease and acute respiratory failure in intensive care units: A case\u2013control study"],"prefix":"10.1177","volume":"16","author":[{"given":"Willy","family":"Chou","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Chi Mei Medical Center, Chiali, Taiwan"},{"name":"Department of Recreation and Health-Care Management, Chia Nan University of Pharmacy and Science, Tainan, Taiwan"},{"name":"Willy Chou and Chih-Cheng Lai contributed equally in this article."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Cheng","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan"},{"name":"Willy Chou and Chih-Cheng Lai contributed equally in this article."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Chen","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan"},{"name":"Department of Safety, Health and Environment, Chung Hwa University of Medical Technology, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Shu","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan"},{"name":"Department of Business Management, National Sun Yat-Sen University, Kaohsiung, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6751-280X","authenticated-orcid":false,"given":"Chin-Ming","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Recreation and Health-Care Management, Chia Nan University of Pharmacy and Science, Tainan, Taiwan"},{"name":"Departmnt of Intensive Care Medicine, Chi Mei Medical Center, Tainan, Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai-Chin","family":"Cheng","sequence":"additional","affiliation":[{"name":"Section of Respiratory Care, Department of Internal Medicine, Chi-Mei Medical Center, Tainan, Taiwan"},{"name":"Department of Medical Sciences Industry, Chang Jung Christian University, Tainan, 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