{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:54:20Z","timestamp":1777532060915,"version":"3.51.4"},"reference-count":39,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Norwegian ExtraFoundation for Health and Rehabilitation","award":["2016\/FO76163"],"award-info":[{"award-number":["2016\/FO76163"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:p>Fatigue is the most prevalent symptom among patients with sarcoidosis, and skeletal muscle dysfunction is a common clinical feature, making resistance training (RT) a recommended treatment strategy. Despite lacking knowledge regarding whether high-intensity RT will aggravate fatigue, low to moderate-intensity is routinely used even if the evidence for this protocol to improve muscle strength is inconclusive. This study aimed to investigate whether one single session of high-intensity RT induces a higher increase in fatigue than one single session of moderate-intensity RT. In this randomized crossover study, 41 patients with pulmonary sarcoidosis (age: 53 \u00b1 11 yr) were recruited. They randomly performed one single session of high-intensity RT, 4 sets \u00d7 5 repetitions maximum (5RM), and one single session of moderate-intensity RT, 2 sets \u00d7 25 RM. Fatigue was assessed with the Visual Analogue Scale (0\u2013100 mm) immediately before (T0), immediately after (T1) and 24 hours after (T2) each exercise session. Fatigue development from T0 to T1 was significantly lower after 5RM (\u22123 \u00b1 18 mm) than after 25RM (5 \u00b1 15 mm), p = 0.004. No difference was seen from T0 to T2 between 5RM (0 \u00b1 17 mm) and 25RM (6 \u00b1 18 mm), p = 0.147. The high-intensity 5RM session did not induce a larger increase in fatigue than the moderate-intensity 25RM session. RT appears feasible and safe in patients with pulmonary sarcoidosis irrespective of the intensity. Thus, the long-term effects of high-intensity RT on fatigue should be explored in a RT programme of longer duration.<\/jats:p>","DOI":"10.1177\/1479973120967024","type":"journal-article","created":{"date-parts":[[2020,12,2]],"date-time":"2020-12-02T04:55:10Z","timestamp":1606884910000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["The acute impact of resistance training on fatigue in patients with pulmonary sarcoidosis"],"prefix":"10.1177","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0582-3431","authenticated-orcid":false,"given":"Anita","family":"Grongstad","sequence":"first","affiliation":[{"name":"LHL Hospital Gardermoen, Jessheim, Norway"},{"name":"Department of Interdisciplinary Health Sciences, University of Oslo, Oslo, Norway"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina 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