{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:54:41Z","timestamp":1777532081234,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Cough is a main symptom in cystic fibrosis (CF). We aim to validate a Spanish version of the Leicester Cough Questionnaire (LCQ-Sp) to measure the impact of cough in CF bronchiectasis. A prospective longitudinal multicentre study was performed. Internal consistency and score changes over a 15-day period in stable state were assessed to analyse reliability. Concurrent validity was analysed by correlation with Saint George\u2019s Respiratory Questionnaire (SGRQ) and convergent validity by assessing the association with clinical variables. Changes in scores between stable state and the first exacerbation were assessed to analyse responsiveness. 132 patients (29.73 \u00b1 10.52 years) were enrolled in four hospitals. Internal consistency was high for the total score and good for the three domains (Cronbach\u2019s \u03b1 0.81\u20130.93). The test\u2013retest reliability showed an intraclass correlation coefficient of 0.86 for the total score. The correlation between LCQ-Sp and SGRQ scores was \u22120.74. The LCQ-Sp score negatively correlated with sputum volume, and the mean score decreased at the beginning of exacerbations (16.04\u00b13.81 vs 13.91\u00b14.29) with a large effect size. The LCQ-Sp is a reliable, repeatable and responsive instrument to assess the impact of cough in CF bronchiectasis and is responsive to change in the event of exacerbations.<\/jats:p>","DOI":"10.1177\/14799731211036903","type":"journal-article","created":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T09:57:10Z","timestamp":1635933430000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Validation of a Spanish version of the Leicester Cough Questionnaire in cystic fibrosis"],"prefix":"10.1177","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5420-0556","authenticated-orcid":false,"given":"Gerard","family":"Mu\u00f1oz","sequence":"first","affiliation":[{"name":"Respiratory Group, Girona Biomedical Research Institute [IDIBGI], Girona, Spain"},{"name":"Departament of Physical Therapy, EUSES, Girona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-1991","authenticated-orcid":false,"given":"Javier","family":"de Gracia","sequence":"additional","affiliation":[{"name":"CIBER of Respiratory Diseases (Ciberes CB06\/06\/0030), Carlos III Health Institute, Madrid, Spain"},{"name":"Department of Respiratory Medicine, Vall d\u2019Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Giron","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Instituto de Investigaci\u00f3n del Hospital de la Princesa, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Casilda","family":"Olveira","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Malaga Regional University Hospital, Instituto de Biomedicina de M\u00e1laga (IBIMA), Universidad de M\u00e1laga, M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Alvarez","sequence":"additional","affiliation":[{"name":"CIBER of Respiratory Diseases (Ciberes CB06\/06\/0030), Carlos III Health Institute, Madrid, Spain"},{"name":"Department of Respiratory Medicine, Vall d\u2019Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Bux\u00f3","sequence":"additional","affiliation":[{"name":"Girona Biomedical Research Institute [IDIBGI], Girona, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surinder S","family":"Birring","sequence":"additional","affiliation":[{"name":"Faculty of Life Sciences & Medicine UK, Centre for Human &Applied Physiological Sciences, School of Basic & Medical Biosciences, King\u2019s College London, London 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