{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:59:30Z","timestamp":1777532370242,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Verona Pharma"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      Treatment recommendations for chronic obstructive pulmonary disease (COPD) are based on single or combination long-acting bronchodilator therapy (\u03b2\n                      <jats:sub>2<\/jats:sub>\n                      -agonists [LABAs] or muscarinic receptor antagonists [LAMAs]), with inhaled corticosteroids (ICS) for those at risk of exacerbations. This study evaluated differences in patient characteristics and treatment patterns among US clinicians.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical record data for patients with COPD were abstracted via a retrospective cross-sectional survey by pulmonologists, internal\/family medicine physicians, nurse practitioners (NPs) and physician assistants (PAs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Data on 700 patients were collected from 175 clinicians: 100 pulmonologists, 45 internal\/family medicine physicians, 30 NP\/PAs. Respondents classified patients as having Mild (11%), Moderate (51%), or Severe\/Very Severe (38%) COPD, with highest perceived disease burden for patients with Severe\/Very Severe COPD. Dual therapies were prescribed differently according to clinician type. Internal\/family medicine physicians and NP\/PAs prescribed LABA\/ICS to a significantly higher proportion of patients than pulmonologists, who favored use of dual bronchodilator therapy. Regardless of clinician type, COPD management was complex, with patients starting and transitioning to multiple treatments throughout their care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Differences in COPD treatment patterns exist across US clinicians. Despite current maintenance treatment, COPD had a profound impact on patients, indicating a need for improved therapies for COPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14799731251346191","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T01:12:08Z","timestamp":1749172328000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Differences in COPD management across clinician type: Maintenance treatment habits and patient characteristics among US pulmonologists, internal\/family medicine physicians, nurse practitioners, and physician assistants"],"prefix":"10.1177","volume":"22","author":[{"given":"Mario","family":"Castro","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, KS, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin C.","family":"Carney","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medicine &amp; Surgery, Temple University Hospital, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven M.","family":"Romanelli","sequence":"additional","affiliation":[{"name":"Trinity Life Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Dixon","sequence":"additional","affiliation":[{"name":"Medical Affairs, Verona Pharma, Raleigh, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam Q.","family":"Abdul Rahman","sequence":"additional","affiliation":[{"name":"Trinity Life Sciences"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavita","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Medical Affairs, Verona Pharma, Raleigh, NC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara P.","family":"Yawn","sequence":"additional","affiliation":[{"name":"Department of Family and Community Health, University of Minnesota, Minneapolis, MN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"e_1_3_5_2_2","unstructured":"Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global strategy for the diagnosis management and prevention of chronic obstructive pulmonary disease (2025 Report). 2025."},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/resp.14007"},{"key":"e_1_3_5_4_2","first-page":"1","volume-title":"Mortality in the United States, 2019","author":"Kochanek KD","year":"2020","unstructured":"Kochanek KD, Xu J, Arias E. Mortality in the United States, 2019. NCHS Data Brief, 2020, pp. 1\u20138."},{"key":"e_1_3_5_5_2","unstructured":"World Health Organization. Global health estimates: leading causes of DALYs. https:\/\/www.who.int\/data\/gho\/data\/themes\/mortality-and-global-health-estimates\/global-health-estimates-leading-causes-of-dalys (2020 accessed 21 November 2024)."},{"key":"e_1_3_5_6_2","unstructured":"American Lung Association. COPD trends brief: burden. https:\/\/www.lung.org\/research\/trends-in-lung-disease\/copd-trends-brief\/copd-burden (accessed 21 November 2024)."},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.3823"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201804-0621CI"},{"key":"e_1_3_5_9_2","volume-title":"Percentage of angina for adults aged 18 and over, United States, 2019\u20142022","author":"National Center for Health Statistics","year":"2018","unstructured":"National Center for Health Statistics. Percentage of angina for adults aged 18 and over, United States, 2019\u20142022. National Health Interview Survey, 2018. https:\/\/wwwn.cdc.gov\/NHISDataQueryTool\/SHS_adult\/index.html (accessed 21 November 2024)."},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S163717"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S265037"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S253812"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-022-02123-5"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00153712"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-4-31"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-3-56"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2020.1776612"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s41030-021-00179-0"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(18)30006-7"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(15)00106-X"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201502-0235LE"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202201-0209PP"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41533-017-0040-z"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2015.12.004"},{"key":"e_1_3_5_25_2","first-page":"415","article-title":"Treatment patterns of chronic obstructive pulmonary disease in employed adults in the United States","volume":"10","author":"Diette GB","year":"2015","unstructured":"Diette GB, Dalal AA, D'Souza AO, et al. 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