{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:59:59Z","timestamp":1777532399516,"version":"3.51.4"},"reference-count":4,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>\n                    Excessive dynamic airway collapse (EDAC) is characterized by abnormal airway collapse during expiration, leading to symptoms such as breathlessness, cough, and reduced quality of life. Treatment options remain limited, and evidence-based guidelines are lacking. This prospective cohort study evaluated the impact of positive airway pressure (PAP) therapy on symptom burden in 23 patients with EDAC referred to a tertiary ventilation centre. Diagnosis was confirmed by computed tomography and\/or bronchoscopy. Patients received nocturnal and ambulatory PAP, with symptom ratings and quality of life assessed at baseline and after three months. PAP therapy produced rapid and sustained improvements in breathlessness, orthopnoea, cough frequency, sleep quality, and quality of life, with significant differences in all domains (\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.01). Adherence to nocturnal PAP was high. These findings suggest that PAP therapy is an effective symptomatic intervention in EDAC and support consideration of EDAC as an indication for PAP therapy in future clinical guidelines.\n                  <\/jats:p>","DOI":"10.1177\/14799731251379038","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:28:16Z","timestamp":1759235296000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Symptomatic improvement in patients with excessive dynamic airway collapse (EDAC) following initiation of positive airway pressure therapy"],"prefix":"10.1177","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7679-0825","authenticated-orcid":false,"given":"Neeraj M.","family":"Shah","sequence":"first","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret","family":"Grovestock","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinjal","family":"Jadeja","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5245-9911","authenticated-orcid":false,"given":"Rebecca","family":"D\u2019Cruz","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Marino","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Ramsay","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelley","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joerg","family":"Steier","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Hart","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eui-Sik","family":"Suh","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick B","family":"Murphy","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Kaltsakas","sequence":"additional","affiliation":[{"name":"Lane Fox Respiratory Service, St Thomas\u2019 Hospital, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Lane Fox Clinical Respiratory Physiology Centre, Guy\u2019s and St Thomas\u2019 NHS Foundation Trust, London, UK"},{"name":"Centre for Human and Applied Physiological Sciences (CHAPS), King\u2019s College London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2164"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.3.984"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00170-2020"},{"issue":"1","key":"e_1_3_3_5_2","first-page":"A113","article-title":"P59 continuous positive airway pressure therapy in patient with excessive dynamic airway collapse: a single centre experience","volume":"77","author":"Hassan MZ","year":"2022","unstructured":"Hassan MZ, Khurana S, Fowler S, et al. P59 continuous positive airway pressure therapy in patient with excessive dynamic airway collapse: a single centre experience. Thorax 2022; 77(Suppl 1): A113.","journal-title":"Thorax"}],"container-title":["Chronic Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14799731251379038","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/14799731251379038","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14799731251379038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:48:26Z","timestamp":1777394906000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/14799731251379038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":4,"alternative-id":["10.1177\/14799731251379038"],"URL":"https:\/\/doi.org\/10.1177\/14799731251379038","relation":{},"ISSN":["1479-9731","1479-9731"],"issn-type":[{"value":"1479-9731","type":"print"},{"value":"1479-9731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"article-number":"14799731251379038"}}