{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T06:59:59Z","timestamp":1777532399492,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The Research Fund for Supporting Lecturer to Admit High Potential Student to Study and Research on His Expert Program Year 2021 of Khon Kaen University","award":["641JH214"],"award-info":[{"award-number":["641JH214"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Chronic obstructive pulmonary disease (COPD) is associated with alterations in brain function that contribute to reduced respiratory and skeletal muscle strength, ultimately limiting exercise capacity. Transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique, has demonstrated efficacy in enhancing lower extremity function in healthy older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the effects of a single session of anodal tDCS on exercise capacity, respiratory muscle strength, and physical performance in individuals with COPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In a randomized, double-blind, sham-controlled trial, 26 participants with COPD underwent baseline assessments of exercise capacity (Six-Minute Walk Distance, 6MWD), respiratory muscle strength (Maximum Inspiratory Pressure, MIP), and physical performance (4-m Gait Speed, 4MGS). Participants then received either active or sham tDCS, followed by reassessment 1\u00a0day post-intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared to sham, the active tDCS group showed significant improvements in physical performance, including increases of 46 \u00b1 11.45\u00a0m in 6MWD (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001), 12.54 \u00b1 4.52 cm, H\n                      <jats:sub>2<\/jats:sub>\n                      O in MIP (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.01), and 0.24 \u00b1 0.08\u00a0m\/s in 4MGS (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A single session of anodal tDCS may enhance exercise capacity, inspiratory muscle strength, and gait speed in patients with COPD, suggesting its potential as a supportive intervention in pulmonary rehabilitation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14799731251383504","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:38:43Z","timestamp":1758847123000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcranial direct current stimulation\u2019s effect on exercise capacity, respiratory muscle strength, and physical performance in patients with chronic obstructive pulmonary disease: Randomized controlled trial"],"prefix":"10.1177","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3761-3727","authenticated-orcid":false,"given":"Chalermkiat","family":"Sawasdee","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand"},{"name":"Noninvasive Brain Stimulation Research Group of Thailand, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1829-2753","authenticated-orcid":false,"given":"Paradee","family":"Auvichayapat","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand"},{"name":"Noninvasive Brain Stimulation Research Group of Thailand, Faculty of Medicine, Khon Kaen University, Khon Kaen, 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