{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T17:57:52Z","timestamp":1784138272903,"version":"3.55.0"},"reference-count":42,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Xiaodiao Zhang","award":["Y20210842"],"award-info":[{"award-number":["Y20210842"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to investigate the associations of the Geriatric Nutritional Risk Index (GNRI) and the simplified Geriatric Nutritional Risk Index (sGNRI) with Chronic Obstructive Pulmonary Disease (COPD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We assessed 161 patients with COPD and 947 healthy controls. The sGNRI was derived using the formula: serum albumin (g\/dL) + 0.1 \u00d7 body mass index (BMI, kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ). Primary outcomes included the BODE (body mass index, airflow obstruction, dyspnea, exercise capacity) index and hospital length of stay (LOS). The secondary outcome was the prevalence of COPD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Malnourished patients (GNRI &lt;95.40 or sGNRI &lt;5.89) exhibited lower BMI and albumin levels, as well as worse pulmonary function (all\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; 0.05). GNRI (Odds Ratio [OR] = 0.945, 95% Confidence Interval [CI]: 0.903-0.989,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.015) and sGNRI (OR = 0.413, 95% CI: 0.191-0.890,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.024) were significantly associated with the severity of COPD in a multivariable-adjusted model. Subgroup analysis revealed stronger predictive performance of GNRI and sGNRI among males, non-hypertensive patients, and smokers (for sGNRI).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with GNRI, sGNRI may serve as a more practical tool for identifying malnutrition-related risk among patients with COPD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14799731251400261","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T09:49:29Z","timestamp":1763545769000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Associations of the geriatric nutritional risk index and simplified geriatric nutritional risk index with chronic obstructive pulmonary disease"],"prefix":"10.1177","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4964-6158","authenticated-orcid":false,"given":"Yiben","family":"Huang","sequence":"first","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruizi","family":"Xu","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanyang","family":"Chen","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyao","family":"Chen","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zicong","family":"Dai","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinran","family":"Li","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiting","family":"Yu","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Ye","sequence":"additional","affiliation":[{"name":"Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianjing","family":"Chen","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyan","family":"Liu","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beibei","family":"Yu","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yage","family":"Xu","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1197-3276","authenticated-orcid":false,"given":"Xiaodiao","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Wenzhou Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,19]]},"reference":[{"key":"e_1_3_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00470-6"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00511-7"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2005.11.023"},{"key":"e_1_3_7_5_2","first-page":"215","article-title":"Nutritional status, dietary intake, and health-related quality of life in outpatients with COPD","volume":"14","author":"Nguyen HT","year":"2019","unstructured":"Nguyen HT, Collins PF, Pavey TG, et al. 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