{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:09:36Z","timestamp":1789992576727,"version":"4.0.1"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Asociaci\u00f3n de Neumologia y Cirugia Tor\u00e1cica del Sur","award":["n 4-2024"],"award-info":[{"award-number":["n 4-2024"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Chron Respir Dis"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prevalence of insomnia in patients with chronic obstructive pulmonary disease (COPD) and evaluate its association with health status, pulmonary function, anxiety\/depression, and exacerbations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional observational study was conducted including consecutive COPD outpatients. Data collected included sociodemographic and clinical variables, daytime sleepiness (Epworth Sleepiness Scale), quality of life (COPD Assessment Test, CAT), anxiety and depression (HADS), insomnia severity (Insomnia Severity Index, ISI), and exacerbations in the previous year. Multivariable logistic regression analysis was performed to identify independent predictors of insomnia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 103 patients (77 males, 26 females) were included. Insomnia prevalence was 38.8% (32.5% mild, 55.0% moderate, 12.5% severe). No significant differences in pulmonary function were observed between patients with and without insomnia. However, patients with insomnia had poorer health status (CAT 19.13\u00b18.63 vs. 11.32\u00b18.13; p&lt;0.001), greater daytime sleepiness (Epworth 5.23\u00b13.10 vs. 3.84\u00b12.31; p&lt;0.011), higher anxiety prevalence (61.5% vs. 31.2%; OR=3.533), and more exacerbations (50% vs. 28.6%; OR=2.5; p&lt;0.037). In multivariable analysis, the CAT score was the only independent predictor of insomnia (OR 1.083; 95% CI 1.011\u20131.160;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.023).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Insomnia is highly prevalent in COPD and is associated with poorer health status, greater daytime sleepiness, increased anxiety, and more frequent exacerbations. Poorer health status was the only independent predictor of insomnia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/14799731261490558","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T10:31:47Z","timestamp":1789727507000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prevalence and impact of insomnia in patients with chronic obstructive pulmonary disease"],"prefix":"10.1177","volume":"23","author":[{"given":"Aureliano","family":"Ais-Daza","sequence":"first","affiliation":[{"name":"Hospital Universitario Puerta del Mar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angel","family":"Carmona-Gonzalez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Puerta del Mar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sof\u00eda","family":"Gutierrez-Hernandez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Puerta del Mar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Castillo-Rivillas","sequence":"additional","affiliation":[{"name":"Hospital Universitario Puerta del Mar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelio","family":"Arnedillo-Lopez","sequence":"additional","affiliation":[{"name":"Hospital Cl\u00ednico Universitario Lozano Blesa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2267-057X","authenticated-orcid":false,"given":"Aurelio","family":"Arnedillo-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Hospital Universitario Puerta del Mar"},{"name":"INiBICA. Instituto de Investigaci\u00f3n e Innovaci\u00f3n Biom\u00e9dica de C\u00e1diz"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2021.03.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31743-3"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(23)00261-8"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2020.07.024"},{"key":"e_1_3_3_6_2","doi-asserted-by":"crossref","unstructured":"L\u00f3pez-Campos JL Almagro P G\u00f3mez TM et al. en nombre del equipo de trabajo de GesEPOC 2021. Actualizaci\u00f3n de la Gu\u00eda Espa\u00f1ola de la EPOC (GeSEPOC: comorbilidades automanejo y cuidados paliativos. Arch Bron-coneumol 2022 vol 58 pp. 334\u2013344.","DOI":"10.1016\/j.arbres.2021.08.002"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40248-015-0023-2"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1556063"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S48570"},{"key":"e_1_3_3_10_2","first-page":"106879","article-title":"Insomnia and its impact on healthcare utilization and costs in patients with chronic obstructive pulmonary disease: A cohort study","volume":"198","author":"Chung F","year":"2022","unstructured":"Chung F, Subramanyam R, Liao P, et al. Insomnia and its impact on healthcare utilization and costs in patients with chronic obstructive pulmonary disease: A cohort study. Respir Med 2022; 198: 106879.","journal-title":"Respir Med"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-2113.168132"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(00)00065-4"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1983.tb09716.x"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00102509"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201908-1590ST"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.5.601"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aprim.2018.02.014"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2010.04.019"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.4103\/atm.ATM_85_20"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10069-0012"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.5005\/IJSM-10-1-11"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.41.11.846"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/26.3.318"},{"key":"e_1_3_3_25_2","first-page":"319","article-title":"Insomnia in older adults with chronic obstructive pulmonary disease (COPD) in Hong Kong: a case-control study","volume":"11","author":"Xiang YT","year":"2014","unstructured":"Xiang YT, Wong TS, Tsoh J, et al. Insomnia in older adults with chronic obstructive pulmonary disease (COPD) in Hong Kong: a case-control study. COPD 2014; 11: 319\u2013324. https:\/\/doi.org\/10.3109\/15412555.2013.858314","journal-title":"COPD"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.12.008"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.1698"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2011.12.007"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0213-9111(99)71404-4"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.adolescence.2009.03.005"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S167678"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-023-02401-w"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2021.101444"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.04.132"}],"container-title":["Chronic Respiratory Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14799731261490558","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/14799731261490558","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/14799731261490558","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:24:29Z","timestamp":1789989869000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/14799731261490558"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":33,"alternative-id":["10.1177\/14799731261490558"],"URL":"https:\/\/doi.org\/10.1177\/14799731261490558","relation":{},"ISSN":["1479-9731","1479-9731"],"issn-type":[{"value":"1479-9731","type":"print"},{"value":"1479-9731","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"article-number":"14799731261490558"}}