{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:56:45Z","timestamp":1791057405925,"version":"4.1.0"},"reference-count":37,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare maternal glucose metrics and pregnancy outcomes of three advanced hybrid closed-loop (aHCL) systems (MiniMed 780G\u00ae, CamAPS\u00ae FX, and Tandem Control-IQ) in a real-world, multicenter cohort of pregnant women with type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Design and Methods:<\/jats:title>\n                    <jats:p>Cohort study including 137 pregnant women with type 1 diabetes using aHCL from 27 hospitals in Spain. Participants were grouped according to the aHCL system used: 85 MiniMed 780G (62%), 38 CamAPS FX (27.7%), and 14 Control-IQ (10.2%). Maternal glucose metrics (HbA1c and time spent within [TIRp], below [TBRp], and above [TARp] the pregnancy-specific glucose range 3.5\u20137.8 mmol\/L), as well as pregnancy outcomes, were analyzed. Adjusted models were applied to account for potential confounding factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      No between-group differences in HbA1c levels were observed at baseline. By the third trimester, CamAPS FX and Control-IQ users had significantly lower HbA1c levels compared with the MiniMed 780G group (\u03b2\n                      <jats:sub>adjusted<\/jats:sub>\n                      \u20134.77 mmol\/mol, 95% confidence interval [CI] \u20137.40 to \u20132.13; and \u03b2\n                      <jats:sub>adjusted<\/jats:sub>\n                      \u20134.79, 95% CI \u20138.53 to \u20131.06; respectively). In the second trimester, CamAPS FX was associated with a higher percentage of time in range (\u03b2\n                      <jats:sub>adjusted<\/jats:sub>\n                      +5.88%, 95% CI 1.09 to 10.67) and a lower percentage of time above range (\u03b2\n                      <jats:sub>adjusted<\/jats:sub>\n                      \u20136.36%, 95% CI \u201311.46 to \u20131.26) compared with MiniMed 780G, with no other significant differences observed in other trimesters. Both CamAPS FX and Control-IQ were associated with lower odds of large-for-gestational-age (LGA) infants (CamAPS FX: OR\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.25, 95% CI 0.08 to 0.77; Control-IQ: OR\n                      <jats:sub>adjusted<\/jats:sub>\n                      0.10, 95% CI 0.01 to 0.99) compared with MiniMed 780G.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In this multicenter observational study, CamAPS FX and Control-IQ users achieved better glycemic metrics and lower odds of delivering LGA infants compared with those using MiniMed 780G. These findings warrant investigation to confirm associations and inform individualized clinical decision-making in pregnant women with type 1 diabetes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15209156251379488","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:40:42Z","timestamp":1758933642000},"page":"327-340","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["A Real-World Study Comparing Advanced Hybrid Closed-Loop Systems During Pregnancy in Women with Type 1 Diabetes"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0423-6446","authenticated-orcid":false,"given":"Carmen","family":"Quir\u00f3s","sequence":"first","affiliation":[{"name":"Hospital Universitari M\u00fatua de Terrassa, Terrassa, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana M.","family":"W\u00e4gner","sequence":"additional","affiliation":[{"name":"Complejo Hospitalario Universitario Insular Materno-Infantil de Canarias, Instituto Universitario de Investigaciones Biom\u00e9dicas y Sanitarias, Universidad de Las Palmas de Gran Canaria, Gran Canaria, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharona","family":"Azriel","sequence":"additional","affiliation":[{"name":"Hospital Universitario Infanta Sof\u00eda, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berta","family":"Soldevila","sequence":"additional","affiliation":[{"name":"Hospital Universitari Germans Trias i Pujol, Institut d\u2019Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol, Badalona, Spain."},{"name":"CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar I.","family":"Beato-Vibora","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Badajoz, Badajoz, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayte","family":"Herrera Arranz","sequence":"additional","affiliation":[{"name":"Hospital Universitario Nuestra Se\u00f1ora de la Candelaria, Santa Cruz de Tenerife, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9758-9397","authenticated-orcid":false,"given":"L\u00eda","family":"Nattero","sequence":"additional","affiliation":[{"name":"CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Madrid, Spain."},{"name":"Hospital Universitario Ram\u00f3n Cajal, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Pic\u00f3n-C\u00e9sar","sequence":"additional","affiliation":[{"name":"Hospital Universitario Virgen de la Victoria, M\u00e1laga, Spain."},{"name":"Biomedical Research Institute-IBIMA Plataforma BIONAND, M\u00e1laga, Spain."},{"name":"CIBER Pathophysiology of Obesity and Nutrition-CIBEROBN, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisenda","family":"Climent","sequence":"additional","affiliation":[{"name":"Hospital del Mar, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2407-1906","authenticated-orcid":false,"given":"Judit","family":"Amig\u00f3","sequence":"additional","affiliation":[{"name":"Hospital Universitari Vall Hebr\u00f3n, Barcelona, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3259-3336","authenticated-orcid":false,"given":"Natalia","family":"Colomo","sequence":"additional","affiliation":[{"name":"CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Madrid, Spain."},{"name":"Hospital Regional Universitario de M\u00e1laga, M\u00e1laga, Spain."},{"name":"Instituto de Investigaci\u00f3n Biom\u00e9dica de M\u00e1laga y Plataforma en Nanomedicina-IBIMA Plataforma BIONAND, M\u00e1laga, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda","family":"Dur\u00e1n-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Hospital Universitario de Getafe, Getafe, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macarena","family":"Alpa\u00f1es Buesa","sequence":"additional","affiliation":[{"name":"Hospital Universitario Puerta del Hierro, Madrid, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Meg\u00eda","sequence":"additional","affiliation":[{"name":"CIBER de Diabetes y Enfermedades Metab\u00f3licas Asociadas (CIBERDEM), Madrid, Spain."},{"name":"Hospital U. 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