{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T12:10:10Z","timestamp":1779883810194,"version":"3.53.1"},"reference-count":33,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T00:00:00Z","timestamp":1763596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The Omnipod\u00ae 5 Automated Insulin Delivery (AID) System is the first wearable, on-body, tubeless AID system in the United States. Clinical trials have demonstrated hemoglobin A1C (HbA1c) improvements with Omnipod 5 use. The aim of the study was to evaluate HbA1c changes after initiating Omnipod 5 in a real-world setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective study utilized commercial and Medicare Advantage with Part D enrollees\u2019 claims data from the Optum Research Database between August 1, 2021, and December 31, 2023. The study included individuals diagnosed with type 1 diabetes (T1D) or type 2 diabetes (T2D) who initiated Omnipod 5. Participants were required to have continuous enrollment for 12 months pre- and post-initiation and at least two medical claims for diabetes during these periods. Demographic and clinical characteristics were measured at the index date, and HbA1c levels were compared pre- and post-initiation of Omnipod 5.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The final sample included 2,504 users, with 792 having pre- and post-initiation HbA1c results. The mean age was 54 years; 48% were enrolled in Medicare Advantage, 90% had prior continuous glucose monitoring, and 64% had prior pump therapy. A mean reduction in HbA1c of 0.4% was observed (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001); mean reductions were 0.4% and 0.5% among those with type 1 and type 2 diabetes, respectively. Among 135 users with pre-initiation HbA1c levels \u22659%, a reduction of 1.4% was noted (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Pre-initiation, 31% achieved the American Diabetes Association (ADA) target of &lt;7% compared to 44% post-initiation (increase of 13%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). For the Healthcare Effectiveness Data and Information Set (HEDIS) target of &lt;8%, 62% of individuals achieved the target pre-initiation compared to 78% post-initiation (increase of 16%;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>In a real-world setting, Omnipod 5 was associated with reduced HbA1c and an increased proportion of individuals achieving ADA and HEDIS glycemic targets.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15209156251395014","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T08:49:09Z","timestamp":1763714949000},"page":"483-489","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Real-World HbA1c Following Initiation of the Omnipod 5 Automated Insulin Delivery System"],"prefix":"10.1177","volume":"28","author":[{"given":"Carol J.","family":"Levy","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes, and Metabolism, The Icahn School of Medicine at Mount Sinai, New York, New York, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Carlow","sequence":"additional","affiliation":[{"name":"Insulet Corporation, Acton, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Swift","sequence":"additional","affiliation":[{"name":"Insulet Corporation, Acton, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Rittgers-Simonds","sequence":"additional","affiliation":[{"name":"Insulet Corporation, Acton, Massachusetts, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noelle N.","family":"Gronroos","sequence":"additional","affiliation":[{"name":"Optum, Eden Prairie, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"Walker","sequence":"additional","affiliation":[{"name":"Optum, Eden Prairie, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin K.","family":"Buysman","sequence":"additional","affiliation":[{"name":"Optum, Eden Prairie, Minnesota, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Forlenza","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Barbara Davis Center for Diabetes, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,11,20]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc25-S007"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2210834"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0255"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2022.0558"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc21-2359"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2205225"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2022.0421"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/pedi.13312"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc21-0172"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32514-9"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2004736"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1907863"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0320"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15470"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.59348"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1089\/dia.2023.0364"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-1550"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S402360"},{"issue":"1","key":"e_1_3_4_20_2","first-page":"S6","article-title":"Summary of revisions: Standards of care in diabetes\u20142025","volume":"48","author":"Committee ADAPP","year":"2025","unstructured":"Committee ADAPP. 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