{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:16:33Z","timestamp":1790806593274,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T00:00:00Z","timestamp":1770595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Technology &amp; Therapeutics"],"published-print":{"date-parts":[[2026,7,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>Real-world evidence (RWE) data on the use of automated insulin delivery (AID) systems in the MENAT region (Middle East, North Africa, T\u00fcrkiye) are limited. The aim of this article is to report RWE data on the use of the MiniMed\u2122 780G AID system in MENAT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>CareLink\u2122 personal data as of July 01, 2024, of MENAT users from countries with more than 25 users were included. Continuous glucose monitoring-based endpoints, system usage, and insulin delivery were examined in (1) the overall cohort, (2) users who reached 12 months of system use (longitudinal cohort), and (3) users having pre- to post-AHCL (advanced hybrid closed-loop) algorithm initiation data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Seven thousand nine hundred and sixty-five users across 19 MENAT countries showed a mean glucose management index (GMI) of 6.9 \u00b1 0.7%, time in range (TIR) of 71.7\u2009\u00b1\u200918.2%, time in tight range (TITR) of 48.9 \u00b1 19.4%, time below range 70 mg\/dL of 2.4\u2009\u00b1\u20093.9%, and time below range 54 mg\/dL of 0.5\u2009\u00b1\u20091.7%. TIR and TITR were higher in users using optimal settings (glucose target\u2009=\u2009100\u2009mg\/dL and an active insulin time\u2009=\u20092\u2009h), being 76.3 \u00b1 16.4% and 54.2 \u00b1 18.8%, respectively. Consistent results were obtained analyzing different age groups, different countries, across the four seasons, between weekday\/weekends, and day\/night. Glycemic improvements began after AHCL algorithm initiation and sustained for 12 months, with a TIR and TBR70 that reached international targets in all months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>MiniMed 780G system RWE data in the MENAT region showed a sustained glycemic control that achieved international target criteria across different age groups, countries, and climate extremes. These findings align with RWE data from other geographies, validate the broad applicability of the MiniMed 780G benefits, and may help expand access to AID systems in the region.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15209156251411940","type":"journal-article","created":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T12:36:10Z","timestamp":1770640570000},"page":"689-696","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Real-World Performance of the MiniMed 780G Advanced Hybrid Closed-Loop System in the Middle East, North Africa, and T\u00fcrkiye Region"],"prefix":"10.1177","volume":"28","author":[{"given":"Mohammed","family":"Al-Sofiani","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Internal Medicine, King Saud University, Riyadh, Saudi Arabia."},{"name":"Division of Endocrinology, Diabetes &amp; Metabolism, Johns Hopkins University, Baltimore, Maryland, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael","family":"Chaar","sequence":"additional","affiliation":[{"name":"Clinical Research and Medical Science, Medtronic Saudi Arabia, Riyadh, Saudi Arabia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"van den Heuvel","sequence":"additional","affiliation":[{"name":"Diabetes Operating Unit, Medtronic International Trading Sarl, Tolochenaz, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ohad","family":"Cohen","sequence":"additional","affiliation":[{"name":"Diabetes Operating Unit, Medtronic International Trading Sarl, Tolochenaz, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goran","family":"Petrovski","sequence":"additional","affiliation":[{"name":"Diabetes Operating Unit, Medtronic International Trading Sarl, Tolochenaz, Switzerland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,9]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"27","article-title":"Review of automated insulin delivery systems for type 1 diabetes and associated time in range outcomes","volume":"18","author":"Nallicheri A","year":"2022","unstructured":"Nallicheri A, , Mahoney KM, , Gutow HA, et al. 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