{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T14:44:16Z","timestamp":1777819456381,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,3,25]],"date-time":"2015-03-25T00:00:00Z","timestamp":1427241600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:p>Purpose: To compare the feasibility and efficacy of recanalizing below-the-knee (BTK) chronic total occlusions (CTOs) between patients with good or poor distal runoff based on magnetic resonance angiography (MRA) scans. Methods: Two hundred long-segment BTK CTOs in 171 limbs of 113 diabetic patients (58 men; mean age 69.8\u00b11.9 years) were divided into good distal runoff (GDR: 119 lesions, 98 limbs) or poor distal runoff groups (PDR: 81 lesions, 73 limbs) based on baseline MRA findings. After angioplasty, modified thrombolysis in myocardial ischemia (mTIMI) grades and ankle-brachial index (ABI) were used to assess immediate outcomes. Regularly scheduled duplex or MRA imaging was performed in follow-up. The restenosis and limb salvage rates were compared. Results: The success rates were 93.3% and 87.7% in the GDR and PDR groups, respectively (p=0.21); subintimal angioplasty was more common in the PDR group (93.0% vs. 63.1%, p&lt;0.01). Completion angiography indicated an mTIMI grade 3 blood flow in 71.2% lesions in the GDR patients and in 52.1% in the PDR (p=0.01) group. Improvement in the ABI was greater in the GDR limbs (p&lt;0.001 vs. PDR). Mean imaging follow-up was 10.8\u00b16.9 months in the GDR group and 11.1\u00b16.6 months in the PDR group. Kaplan-Meier analysis showed a better restenosis-free rate in the GDR group (80.6% vs. 61.7%; p=0.02) at 12 months and for lesions with mTIMI grade 3 flow (p&lt;0.01). At 24 months, Kaplan-Meier analysis revealed a better limb salvage rate in the GDR group (84.2% vs. 54.6%; p=0.02). Conclusion: Distal runoff detected using MRA could be a predictor for successful intraluminal recanalization, better distal tissue perfusion, improved long-term patency, and better limb salvage for patients with BTK CTOs.<\/jats:p>","DOI":"10.1177\/1526602815573229","type":"journal-article","created":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T01:51:16Z","timestamp":1427334676000},"page":"243-251","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Runoff Detected by Magnetic Resonance Angiography as an Indicator for Better Recanalization Outcomes in Below-the-Knee Chronic Total Occlusions in Diabetic Patients"],"prefix":"10.1177","volume":"22","author":[{"given":"Yue-Qi","family":"Zhu","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jue","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua-Qiao","family":"Tan","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hai-Tao","family":"Lu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying-Sheng","family":"Cheng","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Ming","family":"Wei","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-Lei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Gong","family":"Zhao","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University Affiliated Sixth People\u2019s Hospital, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,3,25]]},"reference":[{"key":"bibr1-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.001811"},{"key":"bibr2-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1583\/1545-1550-20.2.149"},{"key":"bibr3-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.01.005"},{"key":"bibr4-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/97382129"},{"key":"bibr5-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2002.01015.x"},{"key":"bibr6-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1177\/1538574410376453"},{"key":"bibr7-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2322030729"},{"key":"bibr8-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1583\/09-2793C1.1"},{"key":"bibr9-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1583\/10-3207.1"},{"key":"bibr10-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1583\/08-2440.1"},{"key":"bibr11-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2422051111"},{"key":"bibr12-1526602815573229","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.04.1111"},{"key":"bibr13-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.119505"},{"key":"bibr14-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-009-1501-8"},{"key":"bibr15-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1097\/01.rli.0000262581.52315.ef"},{"key":"bibr16-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2011.01.013"},{"key":"bibr17-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000094613.61428.a9"},{"key":"bibr18-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1177\/152660280701400404"},{"key":"bibr19-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.06.097"},{"key":"bibr20-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.10.088"},{"key":"bibr21-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1583\/JEVT-12-3998R.1"},{"key":"bibr22-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1053\/j.semvascsurg.2012.03.003"},{"key":"bibr23-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.09.008"},{"key":"bibr24-1526602815573229","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.04.070"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602815573229","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1526602815573229","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602815573229","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:27:59Z","timestamp":1777498079000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1526602815573229"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,25]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1177\/1526602815573229"],"URL":"https:\/\/doi.org\/10.1177\/1526602815573229","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,25]]}}}