{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T14:45:07Z","timestamp":1777819507734,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2015,5,19]],"date-time":"2015-05-19T00:00:00Z","timestamp":1431993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p>Purpose: To assess the effectiveness of drug-eluting balloon (DEB) angioplasty for the treatment of iliac artery in-stent restenosis (ISR). Methods: Data from 18 patients (mean age 59.3\u00b19.6 years; 11 men) treated with DEB for iliac ISR between October 2009 and August 2013 were retrospectively evaluated and compared with a control group of 22 patients (mean age 66.7\u00b111.8 years; 16 men) treated with standard balloon angioplasty (BA). Primary endpoint of the study was the primary patency rate at 12 months. Secondary endpoints were 30-day and overall mortality, sustained clinical improvement [ankle-brachial index (ABI) and Rutherford category] and clinically driven target lesion revascularization (TLR). Follow-up examinations were performed by clinical examination, color duplex ultrasound, and ABI measurement at 12 months. Results: Mean length of the 21 lesions in the DEB group was 27.1\u00b119.2 mm vs 20.0\u00b111.4 mm for the 25 lesions in the BA group (p=0.508), while the grade of restenosis was 70.4%\u00b118.4% and 64.0%\u00b116.1% (p=0.255), respectively. Primary patency rates were 90.5% vs 85.7% at 6 months and 71.4% vs 75.6% at 12 months for DEB and BA, respectively (p=0.784). Five BA patients died during follow-up for reasons unrelated to the procedure, while no patient in the DEB group died (p=0.035). In both groups, Rutherford category and ABI significantly improved compared to pretreatment levels; there were no differences between the groups regarding these variables (p=0.367 and p=0.898, respectively). The TLR rate was 28.6% (6\/21) in the DEB group and 20.0% (4\/20) in the BA cohort (p=0.434). Conclusion: Treatment of iliac ISR using DEBs is a safe procedure, with results comparable to BA treatment. Because of the limited number of patients in this study, further investigation of a larger cohort with longer follow-up is needed to define the role of DEBs in the treatment of iliac ISR.<\/jats:p>","DOI":"10.1177\/1526602815583851","type":"journal-article","created":{"date-parts":[[2015,5,19]],"date-time":"2015-05-19T14:51:06Z","timestamp":1432047066000},"page":"314-318","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Drug-Eluting vs Standard Balloon Angioplasty for Iliac Stent Restenosis"],"prefix":"10.1177","volume":"22","author":[{"given":"Stefan","family":"Stahlhoff","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, St. Franziskus Hospital M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos P.","family":"Donas","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, St. Franziskus Hospital M\u00fcnster, Germany"},{"name":"Department of Vascular and Endovascular Surgery, University of M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Torsello","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, St. Franziskus Hospital M\u00fcnster, Germany"},{"name":"Department of Vascular and Endovascular Surgery, University of M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nani","family":"Osada","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, University of M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Herten","sequence":"additional","affiliation":[{"name":"Department of Vascular and Endovascular Surgery, University of M\u00fcnster, 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