{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T22:45:30Z","timestamp":1777848330722,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T00:00:00Z","timestamp":1545609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>Purpose: To evaluate the incidence and treatment of limb occlusions of the second- and third-generation Anaconda endografts. Methods: A single-center retrospective study was conducted involving 317 consecutive patients (mean age 76 years; 289 men) who underwent endovascular aneurysm repair for elective asymptomatic, symptomatic intact, and ruptured infrarenal abdominal aortic aneurysm with 2 versions of the Anaconda device. From September 2003 to July 2011, the second-generation device was used in 189 patients (mean age 77 years; 169 men) and from July 2011 to September 2015, the third-generation device was implanted in 128 patients (mean age 75 years; 120 men). The rates of limb occlusion were compared between groups and according to compliance with the instructions for use (IFU); predictors were sought in multivariate analysis. The results of the latter are given as the hazard ratio (HR) and 95% confidence interval (CI). Results: Kaplan-Meier freedom of occlusion estimates for second- and third-generation devices, respectively, was 96.6% and 95.0% at 1 year, 89.9% and 95.0% at 2 years, and 86.5% and 88.6% at 5 years. There was no significant difference in overall occlusion rate between the second-generation devices (p=0.332) or with regard to use within the IFU (p=0.827); however, there was a clinically relevant decrease in the occlusion rate for elective patients treated with the third-generation device (6.4% vs 13.1%, p=0.077). There was an increase in the occlusion rate when the iliac limb diameter was \u226413 mm. In multivariate analysis, the only independent predictor of limb occlusion was a small distal prosthesis diameter (HR 0.732, 95% CI 0.63 to 0.86, p&lt;0.001). Symptomatic nonruptured and ruptured abdominal aortic aneurysm (AAA) interventions had an almost 2-fold increased risk of occlusion (HR 1.95, 95% CI 0.93 to 4.11, p=0.078), though this did not reach statistical significance. Conclusion: The Anaconda design has proven effectiveness in AAA exclusion in daily practice inside the IFU. However, efforts could be made to further reduce the limb occlusion rate.<\/jats:p>","DOI":"10.1177\/1526602818821193","type":"journal-article","created":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T04:21:51Z","timestamp":1545625311000},"page":"113-120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Incidence and Treatment of Limb Occlusion of the Anaconda Endograft After Endovascular Aneurysm Repair"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1319-0969","authenticated-orcid":false,"given":"Steffan G. J.","family":"R\u00f6del","sequence":"first","affiliation":[{"name":"Department of Surgery, Martini Hospital, Groningen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clark J.","family":"Zeebregts","sequence":"additional","affiliation":[{"name":"Department of Surgery (Division of Vascular Surgery), University Medical Center Groningen, University of Groningen, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Meerwaldt","sequence":"additional","affiliation":[{"name":"Department of Surgery (Division of Vascular Surgery), Medisch Spectrum Twente, Enschede, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Job","family":"van der Palen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Statistics, Medisch Spectrum Twente, Enschede, the Netherlands"},{"name":"Department of Epidemiology and Statistics, University of Twente, Enschede, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"Geelkerken","sequence":"additional","affiliation":[{"name":"Department of Surgery (Division of Vascular Surgery), Medisch Spectrum Twente, Enschede, the Netherlands"},{"name":"Faculty of Science and Technology, University of Twente, Enschede, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,12,24]]},"reference":[{"key":"bibr1-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2007.01.009"},{"key":"bibr2-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.11.084"},{"key":"bibr3-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2014.04.018"},{"key":"bibr4-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.03.279"},{"key":"bibr5-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2014.09.012"},{"key":"bibr6-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2009.08.007"},{"key":"bibr7-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70045-4"},{"key":"bibr8-1526602818821193","first-page":"111","volume":"24","author":"American Society of Anesthesiologists","year":"1963","journal-title":"Anaesthesiology"},{"key":"bibr9-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2002.123763"},{"key":"bibr10-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2014.04.073"},{"key":"bibr11-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-015-1081-8"},{"key":"bibr12-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2014.03.001"},{"key":"bibr13-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.01.022"},{"key":"bibr14-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(02)00117-9"},{"key":"bibr15-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2005.11.044"},{"key":"bibr16-1526602818821193","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.12.034"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602818821193","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1526602818821193","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602818821193","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:32:56Z","timestamp":1777498376000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1526602818821193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,24]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1177\/1526602818821193"],"URL":"https:\/\/doi.org\/10.1177\/1526602818821193","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,24]]}}}