{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T22:45:31Z","timestamp":1777848331135,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:00:00Z","timestamp":1549843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p>Purpose: To report the 1-year outcomes of a single-center, all-comers registry aimed to assess effectiveness and safety of endovascular revascularization for atherosclerotic erectile dysfunction (ED) in an unselected patient cohort. Materials and Methods: Between April 2016 and October 2017, 50 consecutive patients (mean age 59.6\u00b110.3 years) underwent endovascular revascularization for ED owing to &gt;50% stenosis in 82 erection-related arteries. Patients were treated by means of standard balloon angioplasty (16%), drug-coated balloon angioplasty (27%), or drug-eluting stent (55%) implantation. The primary feasibility outcome measure was the incidence of a minimum clinically relevant improvement of \u22654 in the 6-question International Index of Erectile Function Questionnaire (IIEF-6) score at 12 months. Clinical effectiveness was improvement in erectile function as quantified in the mean difference (MD) of the IIEF-15 score at 3 and 12 months as well as the mean changes in IIEF-15 questions 3 and 4. Results: Procedure success was achieved in 49 (98%) of 50 patients. At 12 months, 30 (65%) of 46 patients achieved a minimum clinically relevant improvement in the IIEF-6 score. The overall IIEF-15 score, as well as scores for questions 3 and 4, improved in 32 (65%) of 49 patients, 28 (57%) of 49 patients, and 29 (60%) of 48 patients, respectively. Change in the overall IIEF-15 score at 12 months was consistent among subgroups, except for elderly patients [MD \u22125.0 (95% CI \u22129.7 to \u22120.2), p=0.041] and those with hypertension [MD \u221211.0 (95% CI \u221220.5 to \u22121.5), p=0.025], who showed less improvement. Conclusion: Endovascular revascularization was safe and efficacious in the majority of ED patients through 1 year.<\/jats:p>","DOI":"10.1177\/1526602819829903","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T05:31:42Z","timestamp":1549863102000},"page":"181-190","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Endovascular Therapy for Erectile Dysfunction\u2014Who Benefits Most? Insights From a Single-Center Experience"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5674-0073","authenticated-orcid":false,"given":"Nicolas","family":"Diehm","sequence":"first","affiliation":[{"name":"Vascular Institute Central Switzerland, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Marggi","sequence":"additional","affiliation":[{"name":"Vascular Institute Central Switzerland, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Ueki","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bern University Hospital, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagmar","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Taefernhof Urology, Baden, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hak Hong","family":"Keo","sequence":"additional","affiliation":[{"name":"Vascular Institute Central Switzerland, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Regli","sequence":"additional","affiliation":[{"name":"Vascular Institute Central Switzerland, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dai Do","family":"Do","sequence":"additional","affiliation":[{"name":"Vascular Institute Central Switzerland, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilmann","family":"Moeltgen","sequence":"additional","affiliation":[{"name":"Department of Urology, Cantonal Hospital Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Grimsehl","sequence":"additional","affiliation":[{"name":"Department of Urology, Cantonal Hospital Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Wyler","sequence":"additional","affiliation":[{"name":"Department of Urology, Cantonal Hospital Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heinz","family":"Schoenhofen","sequence":"additional","affiliation":[{"name":"Center of Radiology Baden, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenz","family":"R\u00e4ber","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Bern University Hospital, Bern, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Schumacher","sequence":"additional","affiliation":[{"name":"Department of Urology, Hirslanden Clinic Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,11]]},"reference":[{"key":"bibr1-1526602819829903","volume":"145","author":"Diehm N","year":"2015","journal-title":"Swiss Med Wkly"},{"key":"bibr2-1526602819829903","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.06.024"},{"key":"bibr3-1526602819829903","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60520-0"},{"key":"bibr4-1526602819829903","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2005.11.2.151"},{"key":"bibr5-1526602819829903","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.08.1016"},{"key":"bibr6-1526602819829903","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV10I1A23"},{"key":"bibr7-1526602819829903","doi-asserted-by":"publisher","DOI":"10.1177\/1526602816669337"},{"key":"bibr8-1526602819829903","unstructured":"Wang TD, Lee WJ, Lin PC, et al. A randomised comparison between drug-eluting balloon and conventional balloon angioplasty for lesions in the penile artery in patients with erectile dysfunction: the PERFECT-4 study. Paper presented at: EuroPCR 2016; May 17\u201320, 2016; Paris, France.\n                      https:\/\/www.tctmd.com\/slide\/randomised-comparison-between-drug-eluting-balloon-and-conventional-balloon-angioplasty\n                      . Accessed January 17, 2018."},{"key":"bibr9-1526602819829903","unstructured":"Wang TD, Lee WJ, Chen WJ, et al. A randomized comparison among drug-eluting balloon, drug-eluting stents, and conventional balloon angioplasty for lesions in the distal internal pudendal artery in patients with erectile dysfunction\u2014the PERFECT-3 study. Paper presented at: TCT 2015; October 11\u201315, 2015; San Francisco, CA, USA.\n                      https:\/\/www.tctmd.com\/slide\/randomized-comparison-among-drug-eluting-balloon-drug-eluting-stents-and-conventional-balloon\n                      . Accessed January 17, 2018."},{"key":"bibr10-1526602819829903","doi-asserted-by":"crossref","unstructured":"Wang TD, Lee WJ, Chen WJ, et al. PERFECT: A prospective registry evaluating the effects of pan-pelvic endovascular intervention on erectile function and lower urinary tract symptoms. Paper presented at: TCT 2016; October 29\u2013November 2, 2016; Washington, DC, USA.\n                      https:\/\/www.tctmd.com\/slide\/perfect-prospective-registry-evaluating-effects-pan-pelvic-endovascular-intervention-erectile\n                      . 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