{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T05:38:50Z","timestamp":1778218730904,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Purpose: To evaluate the perioperative stroke incidence following thoracic endovascular aortic repair (TEVAR) with differing left subclavian artery (LSA) coverage and revascularization approaches in a real-world setting of a nationwide clinical registry. Materials and Methods: The National Surgical Quality Improvement Program registry was interrogated from 2005 to 2017 to identify all nonemergent TEVAR and\/or open LSA revascularization procedures. In this time frame, 2346 TEVAR cases met the selection criteria for analysis. The 30-day stroke incidence was compared between patients undergoing TEVAR with (n=888) vs without (n=1458) LSA coverage, for those with (n=228) vs without (n=660) concomitant LSA revascularization among those with coverage, and following isolated LSA revascularization for occlusive disease (n=768). Multivariable logistic regression was employed for risk-adjusted analyses and to identify factors associated with stroke following TEVAR. Results of the regression analyses are presented as the adjusted odds ratio (OR) with 95% confidence interval (CI). Results: The stroke incidence was 2.3% following TEVAR without vs 5.2% with LSA coverage (p&lt;0.001). In TEVARs with LSA coverage, the stroke incidence was 7.5% when the LSA was concomitantly revascularized and 4.4% without concomitant revascularization, while stroke occurred in 0.5% of isolated LSA revascularizations. Of 33 TEVAR patients experiencing a perioperative stroke, 8 (24%) died within 30 days. LSA coverage was associated with stroke both with concomitant revascularization (OR 4.0, 95% CI 2.2 to 7.5, p&lt;0.001) and without concomitant revascularization (OR 2.2, 95% CI 1.3 to 3.8, p=0.002). Other preoperative factors associated with stroke were dyspnea (OR 1.8, 95% CI 1.1 to 3.0, p=0.014), renal dysfunction (OR 2.2, 95% CI 1.0 to 3.8, p=0.049), and international normalized ratio \u22652.0 (OR 3.6, 95% CI 1.0 to 13, p=0.045). Conclusion: Stroke following TEVAR with LSA coverage occurs frequently in the real-world setting, and concurrent LSA revascularization was not associated with a lower stroke incidence.<\/jats:p>","DOI":"10.1177\/1526602820923044","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T10:40:58Z","timestamp":1590057658000},"page":"769-776","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":34,"title":["Thoracic Endovascular Aortic Repair With Left Subclavian Artery Coverage Is Associated With a High 30-Day Stroke Incidence With or Without Concomitant Revascularization"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1998-5159","authenticated-orcid":false,"given":"Rens R. B.","family":"Varkevisser","sequence":"first","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"},{"name":"Department of Vascular Surgery, Erasmus University Medical Center Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"Swerdlow","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Livia E. V. M.","family":"de Guerre","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirsten","family":"Dansey","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patric","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher A.","family":"Latz","sequence":"additional","affiliation":[{"name":"Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mathijs T.","family":"Carvalho Mota","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hence J. M.","family":"Verhagen","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Erasmus University Medical Center Rotterdam, the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4278-964X","authenticated-orcid":false,"given":"Marc L.","family":"Schermerhorn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"bibr1-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.09.062"},{"key":"bibr2-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.10.050"},{"key":"bibr3-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1177\/152660280701400420"},{"key":"bibr4-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.08.090"},{"key":"bibr5-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1177\/1526602816651417"},{"key":"bibr6-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.10.025"},{"key":"bibr7-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.01.012"},{"key":"bibr8-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.09.031"},{"key":"bibr9-1526602820923044","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-150-9-200905050-00006"},{"key":"bibr10-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.12.075"},{"key":"bibr11-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.03.270"},{"key":"bibr12-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2011.08.009"},{"key":"bibr13-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.08.020"},{"key":"bibr14-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.06.101"},{"key":"bibr15-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2011.03.089"},{"key":"bibr16-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2010.08.013"},{"key":"bibr17-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-012-0997-6"},{"key":"bibr18-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412013312202"},{"key":"bibr19-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.12.063"},{"key":"bibr20-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.05.086"},{"key":"bibr21-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.03.043"},{"key":"bibr22-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.04.045"},{"key":"bibr23-1526602820923044","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.05.036"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602820923044","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1526602820923044","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1526602820923044","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:33:32Z","timestamp":1777498412000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1526602820923044"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,21]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1177\/1526602820923044"],"URL":"https:\/\/doi.org\/10.1177\/1526602820923044","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,21]]}}}