{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:31:58Z","timestamp":1792636318575,"version":"4.5.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T00:00:00Z","timestamp":1678406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To gain insight into safety and efficacy of in situ and ex-situ fenestration techniques for total endovascular arch repair. The term ex-situ fenestration is referring to physician-modified stent-graft technique where fenestration is performed on a back table.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Electronic search was conducted according to PRISMA (Preferred Reporting Items for Systematic review and Meta-analyses) guidelines from 2000 to 2020. The main outcomes measured were 30-day mortality, stroke, aortic-related mortality, and reintervention rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Fifteen studies were eligible: 7 ex-situ fenestration (189 patients) and 8 in-situ fenestration (149 patients). In ex-situ group, dissection was the main pathology treated and proximal sealing zones were Z0 or 1 in 53.5% of patients. In in-situ group, dissection and aneurysm were equally represented in around 40% of cases and proximal sealing zones were Z0 or 1 in 46.5% of patients. Cumulative 30-day all-cause mortality was similar in both groups: 3.8% (95% confidence interval [CI]: 1.7%\u20138.2%) and 3.8% (95% CI: 1.6%\u20138.9%), respectively, in ex-situ and in-situ groups and stroke rate of 2.8% (95% CI: 1.1%\u20137%) and 5.3% (95% CI: 2.6%\u201310.5%). After a 11.1 \u00b1 2.6 months mean follow-up for ex-situ and 16.7 \u00b1 2.3 months for in-situ group, there were 5.2 and 1.4 reinterventions per 100 patients-years, respectively, for ex-situ and in situ groups. Aortic-related mortality rates of, respectively, 3.2% (95% CI: 1.3%\u20137.4%) and 2.6% (95% CI: 0.9%\u20137.3%) were noted in ex-situ and in situ groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The reported data show favorable short-term results of both ex-situ and in-situ fenestration techniques with low mortality and strokes rates. However, durability is still questionable given the lack of long-term data. Both options may have their place in arch repair beyond the spectrum of emergent and urgent cases, on condition that results stand the test of time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Impact<\/jats:title>\n                    <jats:p>In situ and ex-situ fenestration techniques have been initially developed to overcome emergency or as a bail out techniques however giving the promessing favorable short term results indications of these techniques may be extended to elective patients ineligible to customized stent-grafts and possibly in the futur to more elective cases as an option for total endovascular arch repair.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15266028231157639","type":"journal-article","created":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T06:37:05Z","timestamp":1678430225000},"page":"1041-1051","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Systematic Review and Meta-Analysis of Ex-Situ and In-Situ Fenestrated Stent-Grafts for Endovascular Repair of Aortic Arch Pathologies"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2313-4100","authenticated-orcid":false,"given":"Mourad","family":"Boufi","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, Centre Hospitalier Universitaire de Saint-Etienne, Saint-Priest-en-Jarez, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgiana","family":"Alexandru","sequence":"additional","affiliation":[{"name":"APHM, Department of Vascular Surgery, University Hospital Nord, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Tarzi","sequence":"additional","affiliation":[{"name":"APHM, Department of Vascular Surgery, University Hospital Nord, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Molka","family":"Zlitni","sequence":"additional","affiliation":[{"name":"APHM, Department of Vascular Surgery, University Hospital Nord, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houda","family":"Taghi","sequence":"additional","affiliation":[{"name":"APHM, Department of Vascular Surgery, University Hospital Nord, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anderson D.","family":"Loundou","sequence":"additional","affiliation":[{"name":"Department of Public Health, Aix-Marseille Universit\u00e9, Marseille, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,3,10]]},"reference":[{"key":"bibr1-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1161\/circ.100.suppl_2.Ii-316"},{"key":"bibr2-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(03)01023-1"},{"key":"bibr3-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.10.001"},{"key":"bibr4-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1186\/2046-4053-4-1"},{"key":"bibr5-15266028231157639","volume":"328","author":"Atkins D","year":"2004","journal-title":"BMJ"},{"key":"bibr6-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.04.045"},{"key":"bibr7-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/1526602814565776"},{"key":"bibr8-15266028231157639","volume":"40","author":"Katada Y.","year":"2017","journal-title":"Cardiovasc Intervent Radiol"},{"key":"bibr9-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-014-0933-y"},{"key":"bibr10-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2017.11.022"},{"key":"bibr11-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/1708538118807013"},{"key":"bibr12-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.22937"},{"key":"bibr13-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2019.03.016"},{"key":"bibr14-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.07.665"},{"key":"bibr15-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/1526602817714206"},{"key":"bibr16-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2017.11.012"},{"key":"bibr17-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-018-2079-9"},{"key":"bibr18-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/0300060519870903"},{"key":"bibr19-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.07.096"},{"key":"bibr20-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.11.054"},{"key":"bibr21-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1583\/09-2746.1"},{"key":"bibr22-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2018.01.007"},{"key":"bibr23-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.120263"},{"key":"bibr24-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-008-9459-5"},{"key":"bibr25-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/1526602815614557"},{"key":"bibr26-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.07.076"},{"key":"bibr27-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1177\/1526602819865503"},{"key":"bibr28-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.10.061"},{"key":"bibr29-15266028231157639","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2015.06.038"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028231157639","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15266028231157639","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028231157639","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:35:14Z","timestamp":1777498514000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15266028231157639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,10]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1177\/15266028231157639"],"URL":"https:\/\/doi.org\/10.1177\/15266028231157639","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,10]]}}}