{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:18:01Z","timestamp":1793125081142,"version":"4.5.0"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T00:00:00Z","timestamp":1682640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) reconstruction is an endovascular technique, developed to reconstruct the aortic bifurcation in the most optimal anatomical and physiological manner. Short-term data were promising, but long-term data are still lacking. The objective was to report the long-term outcomes of CERAB for extensive aorto-iliac occlusive disease and to identify predictors for loss of primary patency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Consecutive electively treated patients with CERAB for aorto-iliac occlusive disease in a single hospital were identified and analyzed. Baseline and procedural data and follow-up were collected at 6-weeks, 6 months, 12 months, and annually thereafter. Technical success, procedural, and 30-day complications were evaluated, as well as overall survival. Patency and freedom from target lesion revascularization rates were analyzed using Kaplan Meier curves. Uni- and multivariate analysis were performed to identify possible predictors of failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>One hundred and sixty patients were included (79 male). Indication for treatment was intermittent claudication for 121 patients (75.6%) and 133 patients (83.1%) had a TASC-II D lesion. Technical success was obtained in 95.6% of patients and the 30-day mortality rate was 1.3%. The 5-year primary, primary-assisted, and secondary patency rates were 77.5%, 88.1%, and 95.0%, respectively, with a freedom-from clinically driven target lesion revascularization (CD-TLR) rate of 84.4%. The strongest predictor of loss of primary patency of CERAB was a previous aorto-iliac intervention (odds ratio [OR]=5.36 (95% confidence interval [CI]: 1.30; 22.07), p=0.020). In patients not previously treated in the aorto-iliac tract, 5-year primary, primary assisted, and secondary patency rates were 85.1%, 94.4%, and 96.9%, respectively. At 5-year follow-up, an improved Rutherford was found in 97.9% of patients and the freedom from major amputation rate was 100%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The CERAB technique is related to good long-term outcomes, particularly in primary cases. In patients that had prior treatment for aorto-iliac occlusive disease, there were more reinterventions and therefore surveillance should likely be more intense.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Impact<\/jats:title>\n                    <jats:p>The Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) reconstruction was designed to improve outcomes of endovascular treatment of extensive aorto-iliac occlusive disease. At 5-year follow-up clinical improvement was found in 97.9% of patients without major amputations. The 5-year overall primary, primary-assisted, and secondary patency rates were 77.5%, 88.1%, and 95.0%, respectively, with a freedom-from clinically driven target lesion revascularization rate of 84.4%. Significantly better patency rates were observed for patients that were never treated before in the target area. The data implicate that CERAB are a valid treatment option for patients with extensive aorto-iliac occlusive disease. For patients previously treated in the target area, other treatment options might be considered, or more intensive follow-up surveillance is warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15266028231166539","type":"journal-article","created":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T09:07:16Z","timestamp":1682672836000},"page":"110-120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Long-Term Outcomes of the Covered Endovascular Reconstruction of the Aortic Bifurcation (CERAB) Technique in Patients With Aorto-Iliac Occlusive Disease"],"prefix":"10.1177","volume":"32","author":[{"given":"Kaj B.","family":"Rouwenhorst","sequence":"first","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8948-8134","authenticated-orcid":false,"given":"Omar M. A.","family":"Abdelbaqy","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"},{"name":"Department of Vascular Surgery, Assiut University Hospital, Assiut, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne","family":"van der Veen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rianne E.","family":"van Rijswijk","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"},{"name":"Multi-Modality Medical Imaging Group, TechMed Center, University of Twente, Enschede, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7641-1322","authenticated-orcid":false,"given":"Suzanne","family":"Holewijn","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5021-1768","authenticated-orcid":false,"given":"Michel M. P. J.","family":"Reijnen","sequence":"additional","affiliation":[{"name":"Department of Surgery, Rijnstate Hospital, Arnhem, The Netherlands"},{"name":"Multi-Modality Medical Imaging Group, TechMed Center, University of Twente, Enschede, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,4,28]]},"reference":[{"key":"bibr1-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx095"},{"key":"bibr2-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/17085381211018336"},{"key":"bibr3-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.106572"},{"key":"bibr4-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/15266028211028210"},{"key":"bibr5-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/15266028211025028"},{"key":"bibr6-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29920"},{"key":"bibr7-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.09.015"},{"key":"bibr8-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/1526602816673824"},{"key":"bibr9-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.06.112"},{"key":"bibr10-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(97)70045-4"},{"key":"bibr11-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X15597877"},{"key":"bibr12-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2006.12.037"},{"key":"bibr13-15266028231166539","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.15.14794"},{"key":"bibr14-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/1708538119896197"},{"issue":"3","key":"bibr15-15266028231166539","first-page":"383","volume":"54","author":"Goverde PC","year":"2013","journal-title":"J Cardiovasc Surg"},{"key":"bibr16-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.03.432"},{"key":"bibr17-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-017-1703-4"},{"key":"bibr18-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-021-02785-6"},{"key":"bibr19-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/1526602818810535"},{"key":"bibr20-15266028231166539","doi-asserted-by":"publisher","DOI":"10.1177\/1526602817732952"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028231166539","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15266028231166539","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028231166539","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:35:25Z","timestamp":1777498525000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15266028231166539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,28]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1177\/15266028231166539"],"URL":"https:\/\/doi.org\/10.1177\/15266028231166539","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,28]]}}}