{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T22:44:58Z","timestamp":1777848298441,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The aim was to analyze long-term outcomes of thoracic endografts of the Relay group for treating aortic dissections (AD) with respect to the impact of proximal landing zone choice.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The retrospective single-center study included all patients treated by thoracic endovascular aortic repair (TEVAR) for AD with at least 1 Relay endograft (Relay, RelayPlus, Relay non-bare spring (NBS), Relay NBS Plus; Terumo Aortic, Sunrise, Florida) between January 2008 and December 2019. Patients were grouped according to proximal endograft placement: group 1 (G1)\u2014within healthy aorta and group 2 (G2)\u2014outside healthy aorta. Computed tomography angiography (CTA) scans during follow-up (FU) were analyzed with regard to diameter changes of true\/false aortic lumen, proximal\/distal landing zone configuration, bird-beak configuration, endograft migration, and endoleaks. In addition, patient demographics, morbidity\/mortality, and reinterventions during the early and late FU were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      In total, 64 patients (G1: n=23, 15 male, mean age 60\u00b112 years; G2: n=41, 29 male, mean age 62\u00b112 years) were included. In total, 50 patients (78%) had acute AD and 14 (22%) had chronic AD. In total, 48 (75%) of the procedures were urgent\/emergent. In-hospital mortality was 6% (4\/64), and estimated 1- and 6-year survival in G1 vs G2 was 78% (95% CI=0.94-0.63) vs 87% (95% CI=0.98-0.78) and 64% (95 CI=0.89-0.48) vs 80% (95% CI=0.99-0.64) without statistically significant difference G1 vs G2 (p\n                      <jats:sub>multivariate<\/jats:sub>\n                      =0.25). Coronary artery disease (CAD) was a significant risk factor for survival (p=0.0005, HR=6.57 (2.23-18.95)). Peripheral ischemic complications were 7% (n=2) vs 13% (n=5) and 0% vs 5% (n=2) in G1 vs G2. Proximal aneurysm formation during FU and proximal stent graft movement &gt;1.5 mm were found in 9% vs 21 and 52% vs 63% in G1 vs G2. There was a trend for better aortic remodeling in G1 (p\n                      <jats:sub>multivariate<\/jats:sub>\n                      &gt; 0.11).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Proximal TEVAR landing in healthy aorta was associated with fewer peripheral ischemic complications, a lesser risk for stent graft movement &gt;1.5 mm, a tendency for better aortic remodeling, and less proximal aneurysm formation during FU, even if survival differences were not significant. CAD was a major risk factor for long-term mortality and should therefore be taken into account preoperatively whenever possible.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Impact<\/jats:title>\n                    <jats:p>The study results support proximal TEVAR landing in healthy aorta when treating aortic dissections(AD), showing fewer peripheral ischemic complications, a lesser risk for stent graft movement &gt;1.5mm, a tendency for better aortic remodeling and less proximal aneurysm formation during long-term follow-up. The statistically non-significant trend for inferior long-term survival in patients with TEVAR landing in healthy aorta merits further investigation in contemporary cohorts. Finally, the results show that coronary artery disease is a major risk factor for long-term mortality after TEVAR for AD, highlighting the relevance of close monitoring and, whenever possible, preoperative cardiological patient work-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15266028261419985","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T04:58:47Z","timestamp":1774328327000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of the Proximal Landing Zone Quality on TEVAR Outcomes\u201411-Year Real-World Experience with the Relay Stent Graft Family in Aortic Dissections"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2823-8091","authenticated-orcid":false,"given":"Paula Rosalie","family":"Keschenau","sequence":"first","affiliation":[{"name":"Department of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Justus Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nena","family":"Bandzius","sequence":"additional","affiliation":[{"name":"Department of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Justus Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin","family":"Wei\u00df","sequence":"additional","affiliation":[{"name":"Department of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Justus Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rn","family":"Pons-K\u00fchnemann","sequence":"additional","affiliation":[{"name":"Institute of Medical Informatics, Justus Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Kalder","sequence":"additional","affiliation":[{"name":"Department of Adult and Pediatric Cardiovascular Surgery, University Hospital Giessen, Justus Liebig University Giessen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.11.061"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1583\/10-3233MR.1"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.09.050"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.12.032"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/15266028221136450"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/15266028231161489"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2023.12.034"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.02.026"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.11.013"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2010.07.008"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S152194"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivaa171"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.06.219"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2020.07.087"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.06.005"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12165380"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000032944"}],"container-title":["Journal of Endovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028261419985","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15266028261419985","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15266028261419985","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:32:19Z","timestamp":1777498339000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15266028261419985"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,23]]},"references-count":17,"alternative-id":["10.1177\/15266028261419985"],"URL":"https:\/\/doi.org\/10.1177\/15266028261419985","relation":{},"ISSN":["1526-6028","1545-1550"],"issn-type":[{"value":"1526-6028","type":"print"},{"value":"1545-1550","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,23]]},"article-number":"15266028261419985"}}