{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T22:44:56Z","timestamp":1777848296325,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"abstract":"<jats:p>\n                    Thoracic endovascular aortic repair (TEVAR) is a minimally invasive technique for the treatment of thoracic aortic aneurysms (TAA). We hypothesized that alteration of blood hemodynamics in the thoracic aorta caused by stent implantation can possibly lead to hypertension and reduced coronary flow leading to the induction of heart failure (HF). The search in PubMed, Web of Science, Scopus, and the Cochrane library for studies containing data about the occurrence of HF after TEVAR resulted in 1231 articles of which 11 fulfilled the inclusion criteria. A meta-analysis was undertaken with the raw incidence of HF post-implantation as the primary endpoint. This occurred, in the first 30 days, to 684 out of 30,680 total patients (2.23%), and the raw incidence rate of HF was 0.03 [0.02\u20130.04], p&lt;0.001. The random effects model was used because the examined studies had significant heterogeneity (I\n                    <jats:sup>2<\/jats:sup>\n                    =99.999%, \u03c4\n                    <jats:sup>2<\/jats:sup>\n                    =3.905\u00d710\n                    <jats:sup>\u22124<\/jats:sup>\n                    , p&lt;0.001. In addition, significant publication bias was observed (Egger\u2019s test z=2.156, p=0.031). HF may develop in 30 days post-TEVAR possibly because of the increased aortic stiffness and the subsequent heamodynamic alterations which reduce the coronary blood supply. Thus, it may be necessary to initiate early pharmacological intervention while further research with randomized controlled trials with longer follow-up is warranted for the evaluation of the incidence of HF in the long term after TEVAR.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Clinical Impact<\/jats:title>\n                    <jats:p>Our meta-analysis shows that heart failure (HF) can occur in approximately 3% of patients within 30 days after TEVAR, indicating that HF is a clinically relevant but often under-recognized complication. Increased aortic stiffness and subsequent heamodynamic alterations which reduce the coronary blood supply may contribute to the development of HF. Our findings highlight the need for careful peri- and post-operative cardiac monitoring, particularly in patients with pre-existing cardiovascular risk and the need for hemodynamic optimization after stent-graft implantation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15266028261420021","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:45:23Z","timestamp":1771483523000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Heart Failure Rate After Thoracic Endovascular Aortic Repair (TEVAR)"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1547-4095","authenticated-orcid":false,"given":"Amalia I.","family":"Moula","sequence":"first","affiliation":[{"name":"Department of Surgery, \u201cAchillopouleion\u201d General Hospital, Volos, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Spanos","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, University Hospital of Larissa, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9439-3946","authenticated-orcid":false,"given":"Andrew","family":"Xanthopoulos","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Larissa, Faculty of Medicine, University of Thessaly, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kouvelos","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, University Hospital of Larissa, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5422-4187","authenticated-orcid":false,"given":"Orlando","family":"Parise","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, CARIM School for Cardiovascular Disease, University Hospital Maastricht, University of Maastricht, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandro","family":"Gelsomino","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, CARIM School for Cardiovascular Disease, University Hospital Maastricht, University of Maastricht, Maastricht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7406-5427","authenticated-orcid":false,"given":"Grigorios","family":"Giamouzis","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Larissa, Faculty of Medicine, University of Thessaly, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Giannoukas","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, University Hospital of Larissa, Larissa, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"393","volume-title":"Aneurysm","author":"Droc I","year":"2018","unstructured":"Droc I, Droc G, Buzila C, et al. Abdominal aortic aneurysms (AAA). In: Murai Y, ed. Aneurysm. London: IntechOpen; 2018:393\u2013402."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.11.050"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semtcvs.2015.07.006"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181dd869b"},{"key":"e_1_3_2_6_2","first-page":"17","article-title":"Thoracic endovascular aortic repair (TEVAR) for the treatment of aortic diseases: a position statement from the European association for cardio-thoracic surgery (EACTS) and the European society of cardiology (ESC), in collaboration with the European association of percutaneous cardiovascular interventions (EAPCI)","volume":"42","author":"Grabenwoger M","year":"2012","unstructured":"Grabenwoger M, Alfonso F, Bachet J, et al. Thoracic endovascular aortic repair (TEVAR) for the treatment of aortic diseases: a position statement from the European association for cardio-thoracic surgery (EACTS) and the European society of cardiology (ESC), in collaboration with the European association of percutaneous cardiovascular interventions (EAPCI). Eur Heart J. 2012;42:17\u201324.","journal-title":"Eur Heart J"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1714089"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy399"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2115"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.05.005"},{"key":"e_1_3_2_11_2","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation","volume":"350","author":"Shamseer L","year":"2015","unstructured":"Shamseer L, Moher D, Clarke M, et al. 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