{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T17:51:23Z","timestamp":1791568283235,"version":"4.3.4"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:00:00Z","timestamp":1791417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"abstract":"\n Objective:<\/jats:title>\n The introduction of low-profile stent grafts (LPSGs) has proven to be a useful option despite initial concerns. The aim of this study was to analyze and compare the outcomes of standard-profile stent grafts (SPSGs) versus LPSG in a cohort of patients treated for thoracoabdominal (TAAA) and complex abdominal (CAAA) aortic aneurysms.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A multi-center cohort study based on a retrospective analysis of consecutive patients admitted for the treatment of TAAA and CAAA using fenestrated and\/or branched endovascular aneurysm repair (FB-EVAR) was performed. Outcomes were compared in patients treated with LPSG versus SPSG including procedural metrics, technical success (TS), clinical complications, access-related complications, overall survival, stent-graft integrity issues, secondary interventions, sac enlargement, and primary patency of target vessels (TVs).<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 478 patients were included, with a mean age of 71.6\u2009years (\u00b18.96), and 80.3% were male. There were 227 TAAAs and 251 CAAAs, with a median of 4 (interquartile range [IQR]: 4-4) vessels catheterized per patient. Low-profile stent grafts were used in 137 (28.7%) patients and SPSGs in 341 (71.3%) patients. Low-profile stent grafts were more frequently used in patients with previous aortic surgery (44.9% vs 33.6%,\n P<\/jats:italic>\n \u2009=\u2009.022), and the number of TVs treated differed significantly between LPSG and SPSG (4, IQR: 4-4 vs 4, IQR: 3-4;\n P<\/jats:italic>\n \u2009<\u2009.001). Moderate-to-severe iliac calcification was significantly more common in the LPSG group (29.9% [n\u2009=\u200940] vs 18.3% [n\u2009=\u200961],\n P<\/jats:italic>\n \u2009=\u2009.006). The tortuosity index was also higher in the LPSG group (1.35\u2009\u00b1\u20090.23) compared with in the SPSG group (1.29\u2009\u00b1\u20090.16,\n P<\/jats:italic>\n \u2009=\u2009.030). Patients treated with LPSG had a similar TS rate (92.7% vs 95.0%,\n P<\/jats:italic>\n \u2009=\u2009.33). There were no significant differences in postoperative complications. The median follow-up period was 6.9\u2009months (IQR: 0.8-28.7). Regarding persistent or late endoleaks, no statistically significant differences were observed (\n P<\/jats:italic>\n \u2009=\u2009.36). Overall survival (hazard ratio [HR]: 1.06; 95% CI, 0.66-1.71;\n P<\/jats:italic>\n \u2009=\u2009.78) and freedom from reintervention (HR: 1.04; 95% CI, 0.64-1.70;\n P<\/jats:italic>\n \u2009=\u2009.86) were also similar between groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Fenestrated and\/or branched endovascular aneurysm repair with LPSG and SPSG was performed with similar rates of TS and mortality. Low-profile stent grafts were more often used in complex cases with prior aortic repairs and challenging access. Early and mid-term outcomes were comparable, with both devices showing similar safety and effectiveness profiles.<\/jats:p>\n <\/jats:sec>\n \n Clinical Impact<\/jats:title>\n We performed a retrospective, multicenter cohort study including 478 patients, comparing low-profile stent grafts with standard-profile grafts in the treatment of complex aortic aneurysms. Both types of stent grafts demonstrated similar technical success, safety, and effectiveness. Low-profile endografts proved to be a viable option, particularly in more challenging cases.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/15266028261489194","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T10:06:15Z","timestamp":1791453975000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Low-Profile Versus Standard-Profile Endograft for Thoracoabdominal and Complex Abdominal Endovascular Aortic Treatment\u2014Multicenter Cohort Study"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1762-6603","authenticated-orcid":false,"given":"Tiago","family":"Magalh\u00e3es","sequence":"first","affiliation":[{"name":"Vascular Surgery Department, Hospital Santa Maria, Unidade Local de Sa\u00fade de Santa Maria (ULSSM), Lisboa, Portugal"},{"name":"Faculty of Medicine, University of Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8327-6384","authenticated-orcid":false,"given":"Ryan","family":"Gouveia e Melo","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Hospital Santa Maria, Unidade Local de Sa\u00fade de Santa Maria (ULSSM), Lisboa, Portugal"},{"name":"Faculty of Medicine, University of Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Portugal"},{"name":"Vascular Surgery Department, Ludwig Maximilian University Hospital, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0013-7870","authenticated-orcid":false,"given":"Jan","family":"Stana","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Ludwig Maximilian University Hospital, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8013-4433","authenticated-orcid":false,"given":"Nikolaos","family":"Konstantinou","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Ludwig Maximilian University Hospital, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1619-8851","authenticated-orcid":false,"given":"Ruy","family":"Fernandes e Fernandes","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Hospital Santa Maria, Unidade Local de Sa\u00fade de Santa Maria (ULSSM), Lisboa, Portugal"},{"name":"Faculty of Medicine, University of Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4310-9324","authenticated-orcid":false,"given":"Lu\u00eds","family":"Mendes Pedro","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Hospital Santa Maria, Unidade Local de Sa\u00fade de Santa Maria (ULSSM), Lisboa, Portugal"},{"name":"Faculty of Medicine, University of Lisbon, Portugal"},{"name":"Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6313-7595","authenticated-orcid":false,"given":"Nikolaos","family":"Tsilimparis","sequence":"additional","affiliation":[{"name":"Vascular Surgery Department, Ludwig Maximilian University Hospital, Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yasu.2022.04.002"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004982"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2024.02.037"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2020.06.011"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2017.04.063"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(99)00156-7"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2016.01.038"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2022.05.028"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.07.013"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2023.11.002"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.06.005"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.03.010"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2023.01.205"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.10.015"}],"container-title":["Journal 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