{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T17:46:33Z","timestamp":1791740793725,"version":"4.3.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:00:00Z","timestamp":1791417600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Endovasc Ther"],"abstract":"<jats:p>Pulmonary embolism (PE) in pregnancy is a major clinical challenge with potentially fatal maternal and fetal outcomes. Mechanical thrombectomy (MT) offers a promising alternative when thrombolysis is contraindicated, although evidence in pregnancy is limited. We describe a 26-year-old at 29\u2009+\u20095 weeks\u2019 gestation with high-risk PE causing acute right heart failure, successfully treated, achieving rapid hemodynamic recovery, and minimal fetal radiation exposure. A systematic review identified 15 MT cases in pregnancy or peripartum (11 antepartum, 4 postpartum), reporting 100% maternal survival and favorable fetal outcomes in 87% (1 fetal death, 1 abortion). Complications occurred in 40%, including hemolysis, renal failure, and hemorrhagic shock. MT appears to be an effective, potentially life-saving option in selected obstetric patients when performed in experienced centers with multidisciplinary support.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Clinical Impact<\/jats:title>\n                    <jats:p>Mechanical thrombectomy (MT) represents a valuable therapeutic option for high-risk pulmonary embolism in pregnancy when thrombolysis is contraindicated. In this setting, MT allows for rapid reperfusion and hemodynamic stabilization while avoiding the bleeding risks associated with systemic fibrinolysis. Early consideration of MT within a multidisciplinary framework might significantly improve maternal prognosis without compromising fetal safety.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15266028261494954","type":"journal-article","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:56:06Z","timestamp":1791474966000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Mechanical Thrombectomy for High-Risk Pulmonary Embolism in Pregnancy: A Case Report and a Systematic Review of the Literature"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8345-8663","authenticated-orcid":false,"given":"Andrea","family":"Discalzi","sequence":"first","affiliation":[{"name":"Department of Diagnostic Imaging and Interventional Radiology, City of Health and Science University Hospital, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2782-1437","authenticated-orcid":false,"given":"Benedetta","family":"La Delfa","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4047-1873","authenticated-orcid":false,"given":"Floriana","family":"Nardelli","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Interventional Radiology, City of Health and Science University Hospital, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Brino","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging and Interventional Radiology, City of Health and Science University Hospital, Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marinella","family":"Zanierato","sequence":"additional","affiliation":[{"name":"Anesthesiology and Intensive Care Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariella","family":"Maio","sequence":"additional","affiliation":[{"name":"Anesthesiology and Intensive Care Division, Department of Surgical Sciences, City of Health and Science University Hospital, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Marozio","sequence":"additional","affiliation":[{"name":"Gynecology and Obstetrics 1U, Department of Surgical Sciences, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2002-8050","authenticated-orcid":false,"given":"Nicol\u00f2","family":"Montali","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Cardiovascular and Thoracic Department, City of Health and Science University Hospital, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Calandri","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, University of Turin, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0041-1722867"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12081875"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2021.05.019"},{"issue":"3","key":"e_1_3_2_5_2","article-title":"2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism","volume":"54","author":"Konstantinides SV","year":"2019","unstructured":"Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. 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