{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:21:09Z","timestamp":1791858069844,"version":"4.3.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2007,12,1]],"date-time":"2007-12-01T00:00:00Z","timestamp":1196467200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prog Transpl"],"published-print":{"date-parts":[[2007,12]]},"abstract":"<jats:p>Iron is a critical nutrient source and contributes to staphylococcal pathogenesis. We assessed the role of hepatic explant iron overload as a risk factor for Staphylococcus aureus bacteremia in liver transplant recipients. Seven of 13 cases with S aureus bacteremia (53.8%) had hepatic explant iron concentrations that exceeded normal limits (grade \u2265 2). Length of posttransplant intensive care unit stay ( P = .013) and hepatocellular carcinoma as underlying liver disease ( P = .04), but not hepatic explant iron concentration, correlated with a higher risk of S aureus bacteremia after transplantation. However, noncarriers (patients without S aureus nasal carriage) who developed S aureus bacteremia were more likely to have high hepatic iron content; 4 of 7 (57%) noncarriers with high-grade iron content developed S aureus bacteremia but no noncarriers with low-grade iron content did ( P = .07). All noncarriers who became infected had high iron content (grade \u2265 2) of the hepatic explant. A readily quantifiable assessment of hepatic iron at the time of transplantation can potentially identify patients without carriage who may be at risk for early S aureus bacteremia.<\/jats:p>","DOI":"10.1177\/152692480701700412","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T22:58:26Z","timestamp":1484175506000},"page":"332-336","source":"Crossref","is-referenced-by-count":7,"title":["Hepatic Iron Content and the Risk of\n                    <i>Staphylococcus Aureus<\/i>\n                    Bacteremia in Liver Transplant Recipients"],"prefix":"10.1177","volume":"17","author":[{"given":"Nina","family":"Singh","sequence":"first","affiliation":[{"name":"Veterans Affairs Healthcare System, Pittsburgh, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Wannstedt","sequence":"additional","affiliation":[{"name":"Veterans Affairs Healthcare System, Pittsburgh, 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