{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:14:32Z","timestamp":1777940072815,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prog Transpl"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To observe the effect of naloxone on the lung function of potential lung transplant donors with neurogenic pulmonary edema.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design and Interventions<\/jats:title>\n                    <jats:p>\n                      Donors aged 16 to 55 years without any factors to contraindicate lung donation (pneumonia, pulmonary contusion, etc) were included. Ventilator settings were standardized to a tidal volume of 10 to 12 mL\/kg, an FiO\n                      <jats:sub>2<\/jats:sub>\n                      of 0.40, and a respiratory rate that kept PCO\n                      <jats:sub>2<\/jats:sub>\n                      between 35 and 45 mm Hg. Chest physiotherapy, nebulizer treatments, and frequent suctioning were undertaken. Baseline arterial blood gas analysis and an oxygen challenge were performed. The patients were then given 8 to 10 mg of naloxone. Oxygen challenges and arterial blood gas analyses were repeated every 4 to 6 hours. The data were analyzed by using a paired t test, and each patient served as his or her own control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>These interventions were performed on the 19 LifeQuest donors who met the set criteria from July 2002 to July 2004.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The PaO\n                      <jats:sub>2<\/jats:sub>\n                      on the oxygen challenge immediately after administration of naloxone increased from 329 (SD 177) to 363 (SD 191) mm Hg, although the increase from baseline was not significant. The PaO\n                      <jats:sub>2<\/jats:sub>\n                      from the second oxygen challenge (median time, 7 hours after administration of naloxone) increased to 413 (SD 177) mm Hg ( P &lt; .01).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/152692480901900313","type":"journal-article","created":{"date-parts":[[2017,7,17]],"date-time":"2017-07-17T10:12:51Z","timestamp":1500286371000},"page":"267-271","source":"Crossref","is-referenced-by-count":7,"title":["Effects of Administration of Intravenous Naloxone on Gas Exchange in Brain-Dead Lung Donors"],"prefix":"10.1177","volume":"19","author":[{"given":"Christina","family":"Eagan","sequence":"first","affiliation":[{"name":"LifeQuest Organ Recovery Services, Gainesville, Florida (CE, MT), Mayo Clinic, Jacksonville, Florida (CAK), University of Florida College of Medicine, Gainesville, Florida (MAB)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cesar A.","family":"Keller","sequence":"additional","affiliation":[{"name":"LifeQuest Organ Recovery Services, Gainesville, Florida (CE, MT), Mayo Clinic, Jacksonville, Florida (CAK), University of Florida College of Medicine, Gainesville, Florida (MAB)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maher A.","family":"Baz","sequence":"additional","affiliation":[{"name":"LifeQuest Organ Recovery Services, Gainesville, Florida (CE, MT), Mayo Clinic, Jacksonville, Florida (CAK), University of Florida College of Medicine, Gainesville, Florida (MAB)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Thibault","sequence":"additional","affiliation":[{"name":"LifeQuest Organ Recovery Services, Gainesville, Florida (CE, MT), Mayo Clinic, Jacksonville, Florida (CAK), University of Florida College of Medicine, Gainesville, Florida (MAB)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,9,1]]},"reference":[{"key":"bibr1-152692480901900313","unstructured":"Data on Deceased Donor Transplants. http:\/\/www.optn.org. Accessed December 6, 2008."},{"key":"bibr2-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2003.09.010"},{"key":"bibr3-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1097\/MOT.0b013e32805b727c"},{"key":"bibr4-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200207-670SO"},{"key":"bibr5-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199511000-00009"},{"issue":"6","key":"bibr6-152692480901900313","first-page":"1024","volume":"128","author":"Peterson BT","year":"1983","journal-title":"Am Rev Respir Dis."},{"key":"bibr7-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1984.130.2.183"},{"key":"bibr8-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198209000-00010"},{"key":"bibr9-152692480901900313","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-96-5-684_3"},{"key":"bibr10-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2004.07.006"},{"key":"bibr11-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199312000-00028"},{"issue":"4","key":"bibr12-152692480901900313","first-page":"613","volume":"48","author":"Iwai A","year":"1989","journal-title":"Transplantation."},{"key":"bibr13-152692480901900313","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200603-432OC"}],"container-title":["Progress in Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/152692480901900313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/152692480901900313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T05:37:51Z","timestamp":1777700271000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/152692480901900313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["10.1177\/152692480901900313"],"URL":"https:\/\/doi.org\/10.1177\/152692480901900313","relation":{},"ISSN":["1526-9248","2164-6708"],"issn-type":[{"value":"1526-9248","type":"print"},{"value":"2164-6708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,9]]}}}