{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:43:46Z","timestamp":1782787426529,"version":"3.54.5"},"reference-count":30,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Prog Transpl"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>While the benefits of deceased donor kidney transplant versus dialysis are clear, the impact of graft longevity remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Research Questions<\/jats:title>\n                    <jats:p>This study assessed survival between patients with failed grafts and patients who remained on dialysis alone.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>\n                      Utilizing the Organ Procurement and Transplant Network database, adults on dialysis listed for deceased donor kidney transplant between 1\/2005 and 12\/2017 were identified (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009265\u2005280;\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009129\u2005062 [48.7%] transplant;\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009136\u2005218 [51.3%] dialysis alone, not transplanted). A multivariable Cox proportional hazards model incorporating confounding covariates and utilizing transplant status (dialysis alone, functioning graft, failed graft) as a time-varying covariate was constructed. Representative patients were then fit to this model to assess survival probability.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients who underwent transplant experienced a 65% reduction in mortality compared to those remaining on dialysis. However, graft failure (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200919\u2005389, 15.0% of transplants) was associated with a 47% increase in hazard rate compared to dialysis. When an average-risk patient was fit to this model, with transplant 4 years after dialysis initiation, a graft required longevity of 3 years to convey a survival probability benefit at 5 years postoperatively (9 years from waitlisting, 35%) over remaining on dialysis through the same time point (9 years from waitlisting, 32%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results argue for scrutiny of anticipated graft longevity and its expected impact on individual outcomes and advocate for 3-year graft survival as a critical clinical measure for transplant programs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15269248261456508","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:37:36Z","timestamp":1780465056000},"page":"89-96","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Impact of Failed Deceased Donor Kidney Graft Longevity on Mortality"],"prefix":"10.1177","volume":"36","author":[{"given":"William A.","family":"Preston","sequence":"first","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9928-5330","authenticated-orcid":false,"given":"Scott H.","family":"Koeneman","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0534-1608","authenticated-orcid":false,"given":"Mia N.","family":"Brownfield","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devon J.","family":"Pace","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haley","family":"Kittle","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Noueihed","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Altshuler","sequence":"additional","affiliation":[{"name":"University of California San Francisco"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam M.","family":"Frank","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime M.","family":"Glorioso","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Ramirez","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Andreoni","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren R.","family":"Maley","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam S.","family":"Bodzin","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashesh P.","family":"Shah","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"StatPearls [Internet]","author":"Rout P","year":"2025","unstructured":"Rout P, Aslam A. 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