{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T02:43:47Z","timestamp":1782787427322,"version":"3.54.5"},"reference-count":27,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Prog Transpl"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>While lifelong immunosuppressive therapy is pivotal for liver transplant recipients, nonadherence driven by complex biological, psychological, and social challenges remains a significant clinical problem. This study explored recipients\u2019 experiences with immunosuppressive therapy within the framework of the biopsychosocial model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This descriptive qualitative study included 16 liver transplant recipients recruited via purposive sampling at a hospital in the Aegean region of T\u00fcrkiye. Data were collected through in-depth interviews and analyzed using qualitative content analysis. Following an inductive identification of themes, a deductive mapping approach was employed to integrate the findings within the biological, psychological, and social dimensions of the biopsychosocial model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Recipients\u2019 mean age was 54.56\u2009\u00b1\u200913.47 years. The analysis revealed 2 main themes and 7 subthemes. In the biological dimension, recipients viewed medications as a \u201cway to survive,\u201d though physical quality of life was compromised by persistent \u201cside effects.\u201d The psychological dimension was characterized by \u201cdoubts\u201d and \u201cpsychological effects,\u201d where recipients developed hypervigilance toward bodily sensations and experienced anxiety regarding missed doses. Within the social dimension, the theme \u201ca difficult situation\u201d highlighted how rigid medication schedules and fear of infection led to restricted social participation. Recipients described the development of \u201cimproving health and coping behaviors,\u201d utilizing individualized strategies and social supports to maintain adherence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study demonstrates the complex interplay between the biological, psychological, and social dimensions of medication experiences. Although participants view medications as a vital necessity, they experience adherence challenges due to psychological difficulties and social limitations, highlighting the need for holistic support strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15269248261456868","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T17:30:09Z","timestamp":1780507809000},"page":"81-88","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A Qualitative Study on the Experiences Related to Immunosuppressive Therapy in Liver Transplant Recipients"],"prefix":"10.1177","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3401-6807","authenticated-orcid":false,"given":"Adile","family":"Savsar","sequence":"first","affiliation":[{"name":"Izmir University of Economics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3022-9389","authenticated-orcid":false,"given":"Hatice","family":"Ayhan","sequence":"additional","affiliation":[{"name":"Gulhane Faculty of Nursing, University of Health Sciences Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4019-2687","authenticated-orcid":false,"given":"G\u00fclay Aksu","family":"Kul","sequence":"additional","affiliation":[{"name":"Ac\u0131badem City Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2887-1487","authenticated-orcid":false,"given":"Murat","family":"Kilic","sequence":"additional","affiliation":[{"name":"Ac\u0131badem City Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3138\/canlivj-2020-0016"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/2374373521996956"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2022.06.007"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.01.008"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.578887"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.46332\/aemj.785045"},{"key":"e_1_3_2_8_2","unstructured":"World Health Organization. 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