{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:26:22Z","timestamp":1777940782962,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      Zika virus (ZIKV) is primarily transmitted by\n                      <jats:italic toggle=\"yes\">Aedes<\/jats:italic>\n                      mosquitoes, which thrive in tropical regions. However, reports indicate that asymptomatic carriers can inadvertently transmit ZIKV through blood and blood components.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>To evaluate the risk of ZIKV transmission via blood donation, we investigated the prevalence of ZIKV RNA among healthy Thai blood donors over two consecutive rainy seasons. From January 2020 to September 2021, a total of 64,705 blood donations from 56,145 individual donors were screened for ZIKV RNA at Thailand\u2019s National and Regional Blood Centers. Testing was performed using the cobas Zika test, with initially reactive samples subjected to further confirmation via in-house real-time RT-PCR. Donors with confirmed positive results were recalled for follow-up testing. The complete coding genome was sequenced and analyzed phylogenetically to determine the ZIKV strain lineage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>ZIKV RNA was detected in four confirmed-reactive blood donations, equating to a prevalence of 0.006% (95% CI: 0.0000, 0.0002) or approximately 1 in 16,176 donations. These cases originated from four individual donors who were asymptomatic at the time of donation but subsequently developed mild symptoms, which were resolved within a week. Genetic analysis revealed that the identified ZIKV strains belonged to the Asian lineage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The very low prevalence of ZIKV RNA in blood donations from healthy Thai donors over the 20-month study period suggests that routine ZIKV nucleic acid screening for blood donations is not currently warranted.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15303667261419564","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T12:28:46Z","timestamp":1771331326000},"page":"220-225","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Low Prevalence of Zika Virus RNA Among Thai Blood Donors"],"prefix":"10.1177","volume":"26","author":[{"given":"Sineenart","family":"Oota","sequence":"first","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duangnapa","family":"Intharasongkroh","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilaiwan","family":"Saekram","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peeraya","family":"Suriya","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pichanant","family":"Kumsawang","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kriangsak","family":"Chaiwong","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thanunrat","family":"Thongmee","sequence":"additional","affiliation":[{"name":"Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarawut","family":"Khongwichit","sequence":"additional","affiliation":[{"name":"Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sompong","family":"Vongpunsawad","sequence":"additional","affiliation":[{"name":"Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawinee","family":"Kupatawintu","sequence":"additional","affiliation":[{"name":"National Blood Center, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Poovorawan","sequence":"additional","affiliation":[{"name":"Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.13681"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsb1704752"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1413-81232017227.07012017"},{"key":"e_1_3_5_5_1","unstructured":"Bureau of Epidemiology MoPH Thailand. Annual incidence report of Zika virus in Thailand. 2021. 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Information for blood establishments regarding FDA\u2019s determination that Zika virus is no longer a relevant transfusion-transmitted infection and withdrawal of guidance titled \u201cRevised recommendations for reducing the risk of Zika virus transmission by blood and blood components\u201d. 2021. Available from: https:\/\/www.fda.gov\/media\/148549\/download [Last accessed: March30 2024]."},{"key":"e_1_3_5_23_1","unstructured":"U.S. Food and Drug Administration. Revised recommendations for reducing the risk of Zika virus transmission by blood and blood components. 2018. Available from: https:\/\/collections.nlm.nih.gov\/master\/borndig\/101734377\/UCM518213.pdf [Last accessed: March30 2024]."},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.14041"}],"container-title":["Vector-Borne and Zoonotic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15303667261419564","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/15303667261419564","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/15303667261419564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:00:48Z","timestamp":1777701648000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/15303667261419564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,17]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,1]]}},"alternative-id":["10.1177\/15303667261419564"],"URL":"https:\/\/doi.org\/10.1177\/15303667261419564","relation":{},"ISSN":["1530-3667","1557-7759"],"issn-type":[{"value":"1530-3667","type":"print"},{"value":"1557-7759","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,17]]}}}