{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T11:10:04Z","timestamp":1778929804085,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T00:00:00Z","timestamp":1771200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"National Key Research and Development Program of China","award":["2023YFC2605104"],"award-info":[{"award-number":["2023YFC2605104"]}]},{"name":"Xinjiang Tianshan Innovation Team Research Project","award":["2025D14007"],"award-info":[{"award-number":["2025D14007"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Vector-Borne and Zoonotic Diseases"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Small mammals can carry and transmit various virulent pathogens. Xinjiang Uygur Autonomous Region (Xinjiang), with its rich diversity of small mammal species, represents a high-risk region for pathogen transmission. Epidemiological analysis and genetic sequencing of these pathogens are crucial for strengthening public health interventions.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>\n                        <jats:italic toggle=\"yes\">Methods:<\/jats:italic>\n                      <\/jats:bold>\n                      This study examined the analysis of effects of region, habitat, host genus, and climatic factors on pathogen infection rates in small mammals using spleen and lung tissue samples collected between May and September 2024. Categorical variables were assessed using Pearson\n                      <jats:inline-formula>\n                        <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                          <mml:mrow>\n                            <mml:msup>\n                              <mml:mrow>\n                                <mml:mi>\u03c7<\/mml:mi>\n                              <\/mml:mrow>\n                              <mml:mn>2<\/mml:mn>\n                            <\/mml:msup>\n                          <\/mml:mrow>\n                        <\/mml:math>\n                      <\/jats:inline-formula>\n                      test\/Monte Carlo\n                      <jats:inline-formula>\n                        <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" display=\"inline\" overflow=\"scroll\">\n                          <mml:mrow>\n                            <mml:msup>\n                              <mml:mrow>\n                                <mml:mi>\u03c7<\/mml:mi>\n                              <\/mml:mrow>\n                              <mml:mn>2<\/mml:mn>\n                            <\/mml:msup>\n                          <\/mml:mrow>\n                        <\/mml:math>\n                      <\/jats:inline-formula>\n                      test, while continuous variables were analyzed with the Wilcoxon rank-sum test. Principal component analysis was applied to extract key influence factors, followed by binary logistic regression modeling. Pathogens were detected in 43 host animals, including\n                      <jats:italic toggle=\"yes\">Anaplasma phagocytophilum<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 27) and\n                      <jats:italic toggle=\"yes\">Spotted fever group rickettsiae<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"yes\">SFGR<\/jats:italic>\n                      ;\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 15), with infection rate comparisons conducted under different conditions (\n                      <jats:italic toggle=\"yes\">\u03b1<\/jats:italic>\n                      = 0.05). Positive samples were sequenced and subjected to phylogenetic analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The overall pathogen infection rate in small mammals from Xinjiang border ports was 40.19%, comprising\n                      <jats:italic toggle=\"yes\">A. phagocytophilum<\/jats:italic>\n                      (25.23%) and\n                      <jats:italic toggle=\"yes\">SFGR<\/jats:italic>\n                      (14.02%). High temperature, low relative humidity, the Huoerguosi Port, and grassland habitats were associated with a reduced infection rate of pathogenic microorganisms (odds ratio = 0.71, 95% confidence interval = 0.51\u20130.93,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.021). Spatially,\n                      <jats:italic toggle=\"yes\">A. phagocytophilum<\/jats:italic>\n                      showed the highest infection rate in the Dulata Port, desert habitats, and\n                      <jats:italic toggle=\"yes\">Meriones spp.<\/jats:italic>\n                      , whereas\n                      <jats:italic toggle=\"yes\">SFGR<\/jats:italic>\n                      predominated in the Takeshiken Port, alpine meadow steppes, and\n                      <jats:italic toggle=\"yes\">Marmota spp.<\/jats:italic>\n                      Genetic homology analysis revealed maximum sequence similarities of 99.15% for\n                      <jats:italic toggle=\"yes\">A. phagocytophilum<\/jats:italic>\n                      and 98.35% for\n                      <jats:italic toggle=\"yes\">SFGR<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Xinjiang border ports have a high diversity of small mammal species with elevated pathogen infection rates. These findings underscore the necessity for sustained and enhanced surveillance of small mammal-borne diseases in this region.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/15303667261424792","type":"journal-article","created":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T14:36:58Z","timestamp":1771252618000},"page":"313-322","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pathogenic Microorganism Surveillance and Genetic Sequence Analysis of Small Mammals in Xinjiang Border Port Areas, China, 2024"],"prefix":"10.1177","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3274-6426","authenticated-orcid":false,"given":"Duojiao","family":"Li","sequence":"first","affiliation":[{"name":"School of Public Health, Xinjiang Medical University, Urumqi, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Tian","sequence":"additional","affiliation":[{"name":"Xinjiang International Travel Healthcare Center (Urumqi Customs Port Outpatient Department), Urumqi, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoyi","family":"Chen","sequence":"additional","affiliation":[{"name":"Xinjiang International Travel Healthcare Center (Urumqi Customs Port Outpatient Department), Urumqi, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoping","family":"Yin","sequence":"additional","affiliation":[{"name":"Xinjiang International Travel Healthcare Center (Urumqi Customs Port Outpatient Department), Urumqi, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weimin","family":"Xiahou","sequence":"additional","affiliation":[{"name":"Xinjiang International Travel Healthcare Center (Urumqi Customs Port Outpatient Department), Urumqi, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuezheng","family":"Ma","sequence":"additional","affiliation":[{"name":"Institute of Health Inspection and Quarantine, Chinese Academy of Quality and Inspection &amp; Testing, Beijing, People\u2019s Republic of China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,16]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.1001283"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2022.106743"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2024.101264"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1099\/ijsem.0.003963"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwae463"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-025-10775-z"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fvets.2022.895140"},{"key":"e_1_3_3_9_1","volume-title":"StatPearls","author":"Guzman N","year":"2025","unstructured":"Guzman N, , Yarrarapu SNS, , Beidas SO. Anaplasma Phagocytophilum. In: StatPearls. StatPearls Publishing Copyright \u00a9 2025, StatPearls Publishing LLC.: Treasure Island (FL) ineligible companies. Disclosure: Siva Naga Yarrarapu declares no relevant financial relationships with ineligible companies. Disclosure: Sary Beidas declares no relevant financial relationships with ineligible companies., 2025."},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1501598112"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2025.105722"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-012-4002-7"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ttbdis.2020.101478"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2024.110304"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/vbz.2022.0059"},{"issue":"10","key":"e_1_3_3_16_1","first-page":"1153","article-title":"Study on co-infection of tick-borne pathogens in Ixodes persulcatus in Charles Hilary, Xinjiang Uygur autonomous region","volume":"36","author":"Liu X","year":"2015","unstructured":"Liu X, , Zhang G, , Liu R, et al. 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