{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:01:19Z","timestamp":1788411679565,"version":"build-2803163510"},"reference-count":43,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Astrobiology"],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:p>The origin of life is yet a compelling scientific mystery that has sometimes been attributed to high-pressure impacts by small solar system bodies such as comets, meteoroids, asteroids, and transitional objects. High-pressure torsion (HPT) is an innovative method with which to simulate the extreme conditions of astronomical impacts and offers insights relevant to prebiotic chemistry. In the present study, we investigated the polymerization and stability of adenosine monophosphate (AMP), a key precursor to ribonucleic acid (RNA), in dry and hydrated conditions (10 wt% water) under 6 GPa at ambient and boiling water temperatures. Comprehensive analyses with the use of X-ray diffraction, Raman spectroscopy, Fourier-transform infrared spectroscopy, nuclear magnetic resonance, scanning electron microscopy, and matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry revealed no evidence of polymerization, while AMP partly transformed to other organic compounds such as nucleobase-derived fragments of adenine, phosphoribose fragments, dehydrated adenosine, protonated adenosine, and oxidized adenosine. The torque measurements during HPT further highlighted the mechanical behavior of AMP under extreme conditions. These findings suggest that, while HPT under the conditions tested does not facilitate polymerization, the formation of various compounds from AMP confirms the significance of astronomical impacts on the prebiotic chemistry of RNA on early Earth. Key Words: Ribonucleic acid (RNA)\u2014Origin of life\u2014Phase transformations\u2014Chemical reactions\u2014Small solar system bodies. Astrobiology 26, 1\u20139.<\/jats:p>","DOI":"10.1177\/15311074251412318","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T08:40:43Z","timestamp":1768034443000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["High-Pressure Torsion-Induced Transformation of Adenosine Monophosphate: Insights into Prebiotic Chemistry of RNA by Astronomical Impacts"],"prefix":"10.1177","volume":"26","author":[{"given":"Kaveh","family":"Edalati","sequence":"first","affiliation":[{"name":"WPI, International Institute for Carbon Neutral Energy Research (WPI-I2CNER), Kyushu University, Fukuoka, Japan."},{"name":"Mitsui Chemicals, Inc. - Carbon Neutral Research Center (MCI-CNRC), Kyushu University, Fukuoka, Japan."},{"name":"Department of Automotive Science, Graduate School of Integrated Frontier Sciences, Kyushu University, Fukuoka, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Hidalgo-Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"WPI, International Institute for Carbon Neutral Energy Research (WPI-I2CNER), Kyushu University, Fukuoka, Japan."},{"name":"Mitsui Chemicals, Inc. - Carbon Neutral Research Center (MCI-CNRC), Kyushu University, Fukuoka, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanh","family":"Tam Nguyen","sequence":"additional","affiliation":[{"name":"WPI, International Institute for Carbon Neutral Energy Research (WPI-I2CNER), Kyushu University, Fukuoka, Japan."},{"name":"Department of Automotive Science, Graduate School of Integrated Frontier Sciences, Kyushu University, Fukuoka, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,10]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/c1nj20393b"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar200332w"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006758803255"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRev.48.825"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.geoderma.2014.12.016"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2RA05987H"},{"key":"e_1_3_4_8_1","doi-asserted-by":"crossref","unstructured":"Chemical Book. 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